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Review
. 2020 Jun 27;12(6):e8871.
doi: 10.7759/cureus.8871.

The Potential Vaccine Component for COVID-19: A Comprehensive Review of Global Vaccine Development Efforts

Israr Khan  1 , Zahoor Ahmed  2 , Ayesha Sarwar  2 , Abdur Jamil  3 , Faiz Anwer  4
Affiliations
Review

The Potential Vaccine Component for COVID-19: A Comprehensive Review of Global Vaccine Development Efforts

Israr Khan et al. Cureus. .

Abstract

The whole world is concerned about the pandemic of coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), due to fatality of this condition. This has become a public health emergency of international concern. No specific vaccine and medicine have proven effective in large-sized trials at this time. With the rapidly increasing number of positive cases and deaths, there is a dire need for effective treatments and an effective vaccine for prevention. An urgent unmet need led to the planning and opening of multiple drug development trials for treatment and vaccine development. In this article, we have summarized data on cell receptor interactions and data on prospects of new vaccines targeting the deoxyribonucleic acid (DNA), messenger ribonucleic acid (mRNA), and viral minigenes. We have tabulated the available data on various clinical trials testing various aspects of COVID-19 vaccines.

Keywords: coronavirus; covid-19; sars-cov-2; vaccine.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Coronavirus structure.
See this image and copyright information in PMC

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