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. 1977 Jul 15;197(4300):263-5.
doi: 10.1126/science.327545.

A bactericidal effect for human lactoferrin

R R Arnold, M F Cole, J R McGhee

A bactericidal effect for human lactoferrin

R R Arnold et al. Science. .

Abstract

Streptococcus mutans and Vibrio cholerae, but not Escherichia coli, were killed by incubation with purified human apolactoferrin. Concentrations of lactoferrin below that necessary for total inhibition resulted in a marked reduction in viable colony-forming units. This bactericidal effect was contingent upon the metal-chelating properties of the lactoferrin molecule.

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