Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jan-Dec:8:2324709620947267.
doi: 10.1177/2324709620947267.

Cannabis Vaping-Induced Acute Pulmonary Toxicity: Case Series and Review of Literature

Sreedhar Adapa  1 , Vijay Gayam  2 , Venu Madhav Konala  3 , Srinadh Annangi  4 , Mina P Raju  1 , Vishnu Bezwada  1 , Christine McMillan  1 , Hussain Dalal  5 , Amrendra Mandal  2 , Srikanth Naramala  1
Affiliations
Review

Cannabis Vaping-Induced Acute Pulmonary Toxicity: Case Series and Review of Literature

Sreedhar Adapa et al. J Investig Med High Impact Case Rep. 2020 Jan-Dec.

Abstract

The use of cannabis for recreational as well as medicinal use is on the rise recently with more states legalizing it. We conducted a review analysis of the literature published on acute respiratory failure from vaping cannabis oil. We have also summarized the clinical details (age, length of stay, mode of ventilation, common clinical findings, and steroid use) along with common laboratory abnormalities. This article aims to educate health care providers on the clinical manifestations and management strategies for vaping-induced acute respiratory failure. We also discussed the different available formulations of cannabis oil and key ingredients responsible for the vaping-associated lung injury.

Keywords: acute respiratory distress syndrome; acute respiratory failure; cannabidiol; cannabinoid hyperemesis syndrome; cannabis; terpenes; tetrahydrocannabinol.

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Bilateral patchy ground glass opacities in bronchovascular distribution.
Figure 2.
Figure 2.
Mild ground glass opacities to upper lobe with bilateral lower lobe dense consolidations.
Figure 3.
Figure 3.
Bilateral ground glass patchy infiltrates with subpleural sparing and small right pleural effusion.
Figure 4.
Figure 4.
Bilateral upper lobe ground glass opacities centrally distributed.
Figure 5.
Figure 5.
(a) Pretreatment—bilateral upper lobe patchy ground-glass infiltrates. (b) Posttreatment—interval improvement of patchy bilateral upper lobe infiltrates with small residual superior segment right lower lobe ground-glass opacity.
Figure 6.
Figure 6.
Bilateral pleural effusions with peribronchovascular ground glass infiltrates with septal thickening, nodular pattern.
Figure 7.
Figure 7.
Diffuse bilateral ground glass opacities with crazy paving pattern with subpleural sparing.
See this image and copyright information in PMC

References

    1. Florian MLE, Kronkright DP, Norton RE. The Conservation of Artifacts Made From Plant Materials. Getty Publications; 1991.
    1. Andre CM, Hausman JF, Guerriero G. Cannabis sativa: the plant of the thousand and one molecules. Front Plant Sci. 2016; 7:19. - PMC - PubMed
    1. Bonini SA, Premoli M, Tambaro S, et al. Cannabis sativa: a comprehensive ethnopharmacological review of a medicinal plant with a long history. J Ethnopharmacol. 2018;227:300-315. - PubMed
    1. Pellati F, Borgonetti V, Brighenti V, et al. Cannabis sativa L. and nonpsychoactive cannabinoids: their chemistry and role against oxidative stress, inflammation, and cancer. Biomed Res Int. 2018;2018:1691428. - PMC - PubMed
    1. Swanson TE. Controlled substances chaos: the Department of Justice’s new policy position on marijuana and what it means for industrial hemp farming in North Dakota. NDL Rev. 2014;90:599-622.

LinkOut - more resources