Competing interests: KLW reports personal fees from Pfizer, AbbVie, Union Chimique Belge (UCB), Eli Lilly & Company, Galapagos, GlaxoSmithKline (GSK), Roche, Gilead and reports research grants from BMS, Pfizer outside the submitted work. AB and SB have no potential conflicts of interest. PP reports grants from Centers for Disease Control and Prevention, grants from National Center For Advancing Translational Sciences, during the conduct of the study; non-financial support from 3M, personal fees from Eli Lily, outside the submitted work. JB reports personal fees from Pfizer, Lilly, R-Pharm and Viela Bio outside the submitted work. KGS reports grants and personal fees from Amgen, personal fees from Sanofi/Genzyme, personal fees from Gilead, outside the submitted work. CC reports personal fees from AbbVie and is a member of the speakers’ bureau for Sanofi-Regeneron outside the submitted work. LC reports personal fees from Genentech, personal fees from GMS, personal fees from GSK, personal fees from AbbVie, personal fees from Janssen, personal fees from Sanofi, personal fees from Gilead, personal fees from Kiniksa, personal fees from UCB, outside the submitted work. PCR reports personal fees and non-financial support from Roche, personal fees from Abbvie, grants and personal fees from Janssen, grants and personal fees from Novartis, non-financial support from BMS, personal fees from Eli Lilly, personal fees from Pfizer, grants and personal fees from UCB, outside the submitted work. ZSW reports research grants from NIH/NIAMS (K23AR073334 and L30 AR070520) and Bristol-Myers Squibb outside the submitted work. JRC reports grants and personal fees from AbbVie, grants and personal fees from Amgen, grants and personal fees from BMS, grants and personal fees from Corrona, grants and personal fees from Eli Lilly, grants and personal fees from Janssen, grants and personal fees from Myriad, grants and personal fees from Pfizer, grants and personal fees from Regeneron, grants and personal fees from Roche, grants and personal fees from UCB, outside the submitted work.