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. 2020 Sep 14;222(8):1293-1297.
doi: 10.1093/infdis/jiaa472.

Clinical and Epidemiological Features of 46 Children <1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study

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Clinical and Epidemiological Features of 46 Children <1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study

Xinghua Liu et al. J Infect Dis. .

Erratum in

Abstract

The number of coronavirus disease 2019 (COVID-19) cases has exceeded 10 million. However, little is known about the epidemiology and clinical characteristics of COVID-19 infants. We collected medical information of 46 confirmed patients (<1 year old) and retrospectively analyzed epidemiological history, clinical symptoms, and laboratory test results. The median age was 5 (interquartile range, 2-7) months. Sixteen cases had fever and 27 cases had cough. Moderate disease was present in 40 cases and cardiac injury occurred in 38 cases, following by liver dysfunction in 20 cases and lymphocytosis in no cases. Of all infant patients, 2 received invasive mechanical ventilation and 1 died with multiple organ dysfunction syndrome.

Keywords: SARS-CoV-2; children; clinical features; outcome.

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References

    1. Centers for Disease Control and Prevention, Epidemiology Working Group for NCIP Epidemic Response. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China [in Chinese]. Zhonghua Liu Xing Bing Xue Za Zhi 2020; 41:145–51. - PubMed
    1. Zhou P, Yang XL, Wang XG, et al. . A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; 579:270–3. - PMC - PubMed
    1. Li W, Zhang B, Lu J, et al. . The characteristics of household transmission of COVID-19 [manuscript published online ahead of print 17 April 2020]. Clin Infect Dis 2020. doi:10.1093/cid/ciaa450. - PMC - PubMed
    1. Wei WE, Li Z, Chiew CJ, Yong SE, Toh MP, Lee VJ. Presymptomatic transmission of SARS-CoV-2—Singapore, January 23–March 16, 2020. MMWR Morb Mortal Wkly Rep 2020; 69:411–5. - PMC - PubMed
    1. World Health Organization. Coronavirus disease 2019 (COVID-19) situation report–110. Geneva, Switzerland: WHO, 2020.

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