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Comment
. 2020 Nov;33(6):e14142.
doi: 10.1111/dth.14142. Epub 2020 Sep 4.

Cortexolone 17α-propionate for hidradenitis suppurativa

Samuel Antranig Der Sarkissian  1   2 , Helen Yiling Sun  1   3 , Deshan Frank Sebaratnam  1   3
Affiliations
Comment

Cortexolone 17α-propionate for hidradenitis suppurativa

Samuel Antranig Der Sarkissian et al. Dermatol Ther. 2020 Nov.
No abstract available

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References

REFERENCES

    1. Hebert A, Thiboutot D, Stein Gold L, et al. Efficacy and safety of topical clascoterone cream, 1%, for treatment in patients with facial acne: two phase 3 randomized clinical trials. JAMA Dermatol. 2020;156:e200465. https://doi.org/10.1001/jamadermatol.2020.0465.
    1. Goldburg SR, Strober BE, Payette MJ. Hidradenitis suppurativa: epidemiology, clinical presentation, and pathogenesis. J Am Acad Dermatol. 2020;82(5):1045-1058. https://doi.org/10.1016/j.jaad.2019.08.090.
    1. Riis PT, Ring HC, Themstrup L, Jemec GB. The role of androgens and estrogens in hidradenitis suppurativa - a systematic review. Acta Dermatovenerol Croat. 2016;24(4):239-249.
    1. Rosette C, Agan FJ, Mazzetti A, Moro L, Gerloni M. Cortexolone 17α-propionate (clascoterone) is a novel androgen receptor antagonist that inhibits production of lipids and inflammatory cytokines from sebocytes in vitro. J Drugs Dermatol. 2019;18(5):412-418.
    1. Nikolakis G, Kyrgidis A, Zouboulis CC. Is there a role for antiandrogen therapy for hidradenitis suppurativa? A systematic review of published data. Am J Clin Dermatol. 2019;20(4):503-513. https://doi.org/10.1007/s40257-019-00442-w.

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