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Comparative Study
. 2020 Aug 6;20(1):93.
doi: 10.1186/s12880-020-00492-1.

Feasibility study of using simultaneous multi-slice RESOLVE diffusion weighted imaging to assess parotid gland tumors: comparison with conventional RESOLVE diffusion weighted imaging

Jia-Suo Jiang  1 , Liu-Ning Zhu  2 , Qian Wu  1 , Yi Sun  3 , Wei Liu  4 , Xiao-Quan Xu  5 , Fei-Yun Wu  6
Affiliations
Comparative Study

Feasibility study of using simultaneous multi-slice RESOLVE diffusion weighted imaging to assess parotid gland tumors: comparison with conventional RESOLVE diffusion weighted imaging

Jia-Suo Jiang et al. BMC Med Imaging. .

Abstract

Background: To evaluate the feasibility of using simultaneous multi-slice (SMS) readout segmentation of long variable echo-trains (RESOLVE) diffusion-weighted imaging (DWI) to assess parotid gland tumors, compared with conventional RESOLVE DWI.

Methods: From September 2018 to December 2018, 20 consecutive patients with parotid tumors who underwent MRI scan for pre-surgery evaluation were enrolled. SMS-RESOLVE DWI and conventional RESOLVE DWI were scanned with matched imaging parameters, respectively. The scan time of two DWI sequences was recorded. Qualitative (anatomical structure differentiation, lesion display, artifact, and overall image quality) and quantitative (apparent diffusion coefficient, ADC; ratio of signal-to-noise ratio, SNR ratio; ratio of contrast-to-noise ratio, CNR ratio) assessments of image quality were performed, and compared between SMS-RESOLVE DWI and conventional RESOLVE DWI by using Paired t-test. Two-sided P value less than 0.05 indicated significant difference.

Results: The scan time was 3 min and 41 s for SMS-RESOLVE DWI, and 5 min and 46 s for conventional RESOLVE DWI. SMS-RESOLVE DWI produced similar qualitative image quality with RESOLVE DWI (anatomical structure differentiation, P = 0.164; lesion display, P = 0.193; artifact, P = 0.330; overall image quality, P = 0.083). Meanwhile, there were no significant difference on ADCLesion (P = 0.298), ADCMasseter (P = 0.122), SNR ratio (P = 0.584) and CNR ratio (P = 0.217) between two DWI sequences.

Conclusion: Compared with conventional RESOLVE DWI, SMS-RESOLVE DWI could provide comparable image quality using markedly reduced scan time. SMS could increase the clinical usability of RESOLVE technique for DWI of parotid gland.

Keywords: Diffusion-weighted imaging; Magnetic resonance imaging; Parotid gland; Readout segmentation of long variable echo-trains; Simultaneous multi-slice.

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Conflict of interest statement

Not applicable.

Figures

Fig. 1
Fig. 1
Schematic diagram of the placements of ROIs. Based on the DW (b1000) image (a) of a 47-year-old patient with a warthin tumor in the right parotid gland, round regions of interest (ROIs) were drawn in parotid tumors (red), ipsilateral masseter muscle (yellow), ipsilateral spinal cord (green) and background (blue), respectively. The central cystic area was avoided for measurement. Then, the same ROIs were copied on the ADC map (b), and the mean ADC value of tumor and masseter were measured
Fig. 2
Fig. 2
Example of SMS-RESOLVE DWI, RESOLVE DWI, and corresponding ADC maps of a 29-year-old patient with a lymphoepithelioma in the right parotid gland. The tumor showed isointensity on T1-weighted image (a), hyperintensity on T2-weighted image (b), and peripheral hyperintensity and central hypointensity on axial DWI (c, SMS-RESOLVE DWI; d, RESOLVE DWI). Image quality scores were similar for SMS-RESOLVE DWI and conventional RESOLVE DWI. The ADC value of the tumor derived from SMS-RESOLVE DWI (e) and RESOLVE DWI (f) were 0.54 × 10− 3 mm2/s and 0.52× 10− 3 mm2/s, respectively
Fig. 3
Fig. 3
Example of SMS-RESOLVE DWI, RESOLVE DWI, and corresponding ADC maps of a 57-year-old patient with bilateral warthin tumors in parotid glands. The tumor showed slight hyperintensity on T1-weighted image (a), hyperintensity on T2-weighted image (b), and hyperintensity on axial DWI (c, SMS-RESOLVE DWI; d, RESOLVE DWI). Image quality scores were similar for SMS-RESOLVE DWI and RESOLVE DWI. The ADC value of the tumor derived from SMS-RESOLVE DWI (e) and RESOLVE DWI (f) were 0.61 × 10− 3 mm2/s and 0.62× 10− 3 mm2/s, respectively
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