Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jul 20:2020:1763931.
doi: 10.1155/2020/1763931. eCollection 2020.

Asymptomatic Bacteriuria among Pregnant Women Attending Antenatal Care at Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia: Magnitude, Associated Factors, and Antimicrobial Susceptibility Pattern

Mekuria Edae  1 , Zelalem Teklemariam  2 , Fitsum Weldegebreal  2 , Degu Abate  2
Affiliations

Asymptomatic Bacteriuria among Pregnant Women Attending Antenatal Care at Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia: Magnitude, Associated Factors, and Antimicrobial Susceptibility Pattern

Mekuria Edae et al. Int J Microbiol. .

Abstract

Background: Asymptomatic bacteriuria is one of the major risk factors for the development of urinary tract infections during pregnancy which accounts for about 70% of the cases. However, there is no guideline which recommends routine screening of pregnant women for asymptomatic bacteriuria in most of developing countries including Ethiopia. Thus, the aim of this study was to determine the magnitude, associated factors, and antimicrobial susceptibility pattern of asymptomatic bacteriuria among pregnant women.

Methods: A cross-sectional study was conducted from March to April 2019. Data were collected through face-to-face interview and analyzed using Statistical Package for Social Science version 22. A test of association was performed using logistic regression and P value less than 0.05 was considered statistically significant.

Results: The overall prevalence of asymptomatic bacteriuria was 19.9%. Direction of wiping after genital wash, postcoital urination, and catheterization were factors significantly associated with asymptomatic bacteriuria. Most of the isolated Gram positive were highly sensitive to Ceftriaxone (90.9%). Coagulase-negative staphylococci showed higher sensitivity to Augmentin (75.0) and Ceftriaxone (87.5%), whereas they showed resistance to Clindamycin (68.7%) and Ampicillin (62.5%). Gram-negative bacteria isolates showed higher sensitivity to Ceftriaxone (88.2%), Gentamycin (67.5%), and Augmentin (64.7%), while they showed resistance to Ampicillin (70.5%) and Clindamycin (50.0%).

Conclusion: The overall prevalence of asymptomatic bacteriuria among pregnant women in this study was high. Direction of wiping after genital wash, catheterization, and postcoital urination increases the odds of asymptomatic bacteriuria. Therefore, health education on the predisposing factors is strongly recommended.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflicts of interest.

References

    1. Bose A. M., Sreekumary P. K., Pulikkottil S. K. Microbiological profile of asymptomatic bacteriuria in pregnancy. International Journal of Reproduction Gynecol. 2017;6(4):p. 1352. doi: 10.18203/2320-1770.ijrcog20171391. - DOI
    1. Ned C. B., Petitti M., DeWitt T. G., Russell H. Screening for asymptomatic bacteriuria in adults: U.S. Preventive services task force reaffirmation recommendation statement. Annals of Internal Medicine. 2008;149(4) doi: 10.7326/0003-4819-149-1-200807010-00009. - DOI - PubMed
    1. Mwei M. K., Mchome B., John B., Maro E. Asymptomatic bacteriuria among pregnant women attending antenatal clinic at Kilimanjaro Christian Medical Centre in Northern Tanzania. Clinical Practice. 2016;15(6):917–922. doi: 10.4172/clinical-practice.1000427. - DOI
    1. Robina A., Uzma A., Kausar S. Asymptomatic bacteriuria among pregnant women. APMC. 2011;5(7)
    1. Tadesse S., Kahsay T., Adhanom G., et al. Prevalence, antimicrobial susceptibility profile and predictors of asymptomatic bacteriuria among pregnant women in Adigrat General Hospital, Northern Ethiopia. BMC Research Notes. 2018;11(1):p. 740. doi: 10.1186/s13104-018-3844-1. - DOI - PMC - PubMed

LinkOut - more resources