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. 2020 Jul 4:24:100448.
doi: 10.1016/j.eclinm.2020.100448. eCollection 2020 Jul.

Characteristics, risk factors and outcomes among the first consecutive 1096 patients diagnosed with COVID-19 in Kuwait

Sulaiman Almazeedi  1 , Sarah Al-Youha  1 , Mohammad H Jamal  1 , Mohannad Al-Haddad  1 , Ali Al-Muhaini  1 , Fahad Al-Ghimlas  2 , Salman Al-Sabah  1
Affiliations

Characteristics, risk factors and outcomes among the first consecutive 1096 patients diagnosed with COVID-19 in Kuwait

Sulaiman Almazeedi et al. EClinicalMedicine. .

Abstract

Background: In Kuwait, prior to the first case of COVID-19 being reported in the country, mass screening of incoming travelers from countries with known outbreaks was performed and resulted in the first identified cases in the country. All COVID-19 cases at the time and subsequently after, were transferred to a single center, Jaber Al-Ahmad Al-Sabah Hospital, where the patients received standardized investigations and treatments. The objective of this study was to characterize the demographics, clinical manifestations, and outcomes in this unique patient population.

Methods: This retrospective cohort study was conducted between 24th February 2020 and 20th April 2020. All consecutive patients in the entire State of Kuwait diagnosed with COVID-19 according to WHO guidelines and admitted to Jaber Al-Ahmad Al-Sabah Hospital were included. Patients received standardized investigations and treatments. Multivariable analysis was used to determine the associations between risk factors and outcomes (admission to intensive care and/or mortality).

Findings: Of 1096 patients, the median age was 41 years and 81% of patients were male. Most patients were asymptomatic on admission (46.3%), of whom 35 later developed symptoms, and 59.7% had no signs of infection. Only 3.6% of patients required an ICU admission and 1.7% were dead at the study's cutoff date. On multivariable analysis, the risk factors found to be significantly associated with admission to intensive care were age above 50 years old, a qSOFA score above 0, smoking, elevated CRP and elevated procalcitonin levels. Asthma, smoking and elevated procalcitonin levels correlated significantly with mortality in our cohort.

Keywords: COVID-19; Clinical outcomes; Risk factors; SARS-CoV-2.

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References

    1. Guan W.-.J., Ni Z.-.Y., Hu Y. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020 doi: 10.1056/NEJMoa2002032. - DOI - PMC - PubMed
    1. Richardson S., Hirsch J.S., Narasimhan M. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA. 2020 doi: 10.1001/jama.2020.6775. - DOI - PMC - PubMed
    1. Zhou F., Yu T., Du R. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020 doi: 10.1016/S0140-6736(20)30566-3. - DOI - PMC - PubMed
    1. World Health Organization . WHO; 2020. Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected.
    1. Seymour C.W., Liu V.X., Iwashyna T.J. Assessment of clinical criteria for sepsis for the third international consensus definitions for sepsis and septic shock (sepsis-3) J Am Med Assoc. 2016 doi: 10.1001/jama.2016.0288. - DOI - PMC - PubMed