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. 2020 Oct;43(10):748-751.
doi: 10.1097/COC.0000000000000741.

Pelvic Reirradiation Utilizing Pulsed Low-dose Rate Radiation Therapy

Jonathan J Paly  1 , Mengying Deng  2 , Charles T Lee  1 , Shelly B Hayes  1 , Thomas J Galloway  1 , Mark A Hallman  1 , Stephanie E Weiss  1 , Eric M Horwitz  1 , Robert A Price  1 , C-M Charlie Ma  1 , Joshua E Meyer  1
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Pelvic Reirradiation Utilizing Pulsed Low-dose Rate Radiation Therapy

Jonathan J Paly et al. Am J Clin Oncol. 2020 Oct.

Abstract

Pulsed low-dose rate radiation therapy has been shown to reduce normal tissue damage while decreasing DNA damage repair in tumor cells. In a cohort of patients treated with palliative or definitive pelvic reirradiation using pulsed low-dose rate radiation therapy, we observed substantial local control and low rates of toxicity.

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References

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