Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Dec 18;22(12):1882-1883.
doi: 10.1093/neuonc/noaa186.

Letter regarding "Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas"

Jubayer A Hossain  1   2 , Hrvoje Miletic  1   2
Affiliations
Comment

Letter regarding "Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas"

Jubayer A Hossain et al. Neuro Oncol. .
No abstract available

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Tumor recurrence after suicide gene therapy. (A‒D) Hematoxylin and eosin (H&E) stainings of 4 recurrent and invasive tumors in the mesencephalon/pons. Arrows indicate virtual tumor borders. (E) H&E staining of a small tumor lesion with invasive tumor cells at the primary site (cerebrum) from one animal with the main tumor recurrence in the pons/mesencephalon. Arrows indicate virtual tumor border. (F) H&E staining of a primary tumor in the cerebrum of one control animal showing a typical GBM phenotype with palisading necrosis.
See this image and copyright information in PMC

Comment on

References

    1. Drumm MR, Dixit KS, Grimm S, et al. Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas. Neuro Oncol. 2020;22(4):470–479. - PMC - PubMed
    1. Hossain JA, Latif MA, Ystaas LAR, et al. Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma. Neuro Oncol. 2019;21(7):890–900. - PMC - PubMed
    1. Talasila KM, Soentgerath A, Euskirchen P, et al. EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis. Acta Neuropathol. 2013;125(5):683–698. - PMC - PubMed
    1. Lee J, Kotliarova S, Kotliarov Y, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell. 2006;9(5):391–403. - PubMed