Kawasaki disease fact check: Myths, misconceptions and mysteries
- PMID: 32770807
- DOI: 10.1111/jpc.15101
Kawasaki disease fact check: Myths, misconceptions and mysteries
Abstract
Kawasaki disease (KD) is an important cause of childhood vasculitis and a common cause of acquired heart disease in children world-wide. The emergence of Paediatric Multisystem Inflammatory Syndrome-Temporally Associated with SARS-CoV-2, a KD-like hyperinflammatory syndrome and the recent death of Dr Tomisaku Kawasaki make this a timely review. Although KD was described by Dr Kawasaki over 50 years ago, there is still no specific diagnostic test and the aetiology remains elusive. This article summarises the latest evidence, highlights important myths and misconceptions and discusses some of the mysteries that surround this disease.
Keywords: COVID-19; Kawasaki disease; general paediatrics; infectious diseases; intravenous immunoglobulin.
© 2020 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).
References
-
- Kawasaki T. Infantile acute febrile mucocutaneous lymph node syndrome with specific desquamation of the fingers and toes. Clinical observation of 50 cases. Jpn J. Allerg. 1967; 16: 178-222 (in Japanese with English abstract).
-
- Schudel M. Tomisaku Kawasaki, doctor who identified inflammatory disease in children, dies at 95. The Washington Post 2020; 14 Jun 14. Available from: https://www.washingtonpost.com/local/obituaries/tomisaku-kawasaki-doctor... [accessed 15 June 2020].
-
- McCrindle BW, Rowley AH, Newburger JW et al. Diagnosis, treatment, and long-term management of Kawasaki disease: A scientific statement for health professionals from the American Heart Association. Circulation 2017; 135: e927.
-
- Ae R, Makino N, Kosami K, Kuwabara M, Matsubara Y, Nakamura Y. Epidemiology, treatments, and cardiac complications in patients with Kawasaki disease: The nationwide survey in Japan, 2017-2018. J. Pediatr. 2020. https://doi.org/10.1016/j.jpeds.2020.05.034.
-
- Saundankar J, Yim D, Itotoh B et al. The epidemiology and clinical features of Kawasaki disease in Australia. Pediatrics 2014; 133: e1009-14.
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