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Review
. 2021 Feb;19(1):e37-e40.
doi: 10.1016/j.clgc.2020.07.009. Epub 2020 Jul 16.

Synchronous Malignancies Identified by 18F-fluciclovine Positron Emission Tomography for Prostate Cancer: Case Series and Mini-Review

John M Hoyle  1 , Andrew Lenzie  1 , Samuel J Galgano  2 , Jonathan E McConathy  2 , Soroush Rais-Bahrami  3 , Jeffrey W Nix  3 , Andrew M McDonald  4
Affiliations
Review

Synchronous Malignancies Identified by 18F-fluciclovine Positron Emission Tomography for Prostate Cancer: Case Series and Mini-Review

John M Hoyle et al. Clin Genitourin Cancer. 2021 Feb.

Abstract

Positron emission tomography using the fluorine-18 (18F) fluciclovine radiotracer has been approved for use in recurrent prostate cancer and is a useful tool for clinical decision making. However, 18F-fluciclovine is not specific for prostate cancer tumor cells, and false-positive results have been reported. In the present study, we have reported our experience with synchronous malignancies identified using 18F-fluciclovine and reviewed other reported cases, with a special emphasis on highlighting the clinical decisions that led to the correct diagnosis.

Keywords: Cancer imaging; Diagnosis; Fluorine-18 fluciclovine; Positron emission tomography; Synchronous malignancy.

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