Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection
- PMID: 32771919
- PMCID: PMC7395301
- DOI: 10.1016/j.dsx.2020.07.054
Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection
Abstract
Background and aims: The number of positive and death cases from coronavirus disease 2019 (COVID-19) is still increasing. The identification of risk factors for severe outcomes is important. Dyslipidemia has been shown as a long-known risk factor for cardiovascular disease. The aim of this study is to analyze the potential association between dyslipidemia and the severity of COVID-19 infection.
Methods: We systematically searched the PubMed database using specific keywords related to our aims until July 9th, 2020. All articles published on COVID-19 and dyslipidemia were retrieved. Statistical analysis was done using Review Manager 5.4 software.
Results: A total of 7 studies with a total of 6922 patients were included in our analysis. Our meta-analysis showed that dyslipidemia is associated with severe COVID-19 infections [RR 1.39 (95% CI 1.03-1.87), p = 0.03, I2 = 57%, random-effect modelling].
Conclusion: Dyslipidemia increases the risk of the development of severe outcomes from COVID-19 infections. Patients with dyslipidemia should be monitored closely to minimize the risk of COVID-19.
Keywords: COVID-19; Coronavirus disease 2019; Dyslipidemia; Metabolic disease; Metabolic syndrome.
Copyright © 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved.
Conflict of interest statement
Declaration of competing interest The authors declare no conflict of interest regarding this article.
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- Zhang J.J., Dong X., Cao Y.Y., Yuan Y.D., Yang Y.B., Yan Y.Q., Akdis C.A., Gao Y.D. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy. 2020;75(7):1730–1741. - PubMed
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