Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Oct 15;30(3):030402.
doi: 10.11613/BM.2020.030402. Epub 2020 Aug 5.

Laboratory markers included in the Corona Score can identify false negative results on COVID-19 RT-PCR in the emergency room

Affiliations

Laboratory markers included in the Corona Score can identify false negative results on COVID-19 RT-PCR in the emergency room

Roberto Assandri et al. Biochem Med (Zagreb). .

Abstract

After December 2019 outbreak in China, the novel Coronavirus infection (COVID-19) has very quickly overflowed worldwide. Infection causes a clinical syndrome encompassing a wide range of clinical features, from asymptomatic or oligosymptomatic course to acute respiratory distress and death. In a very recent work we preliminarily observed that several laboratory tests have been shown as characteristically altered in COVID-19. We aimed to use the Corona score, a validated point-based algorithm to predict the likelihood of COVID-19 infection in patients presenting at the Emergency rooms. This approach combines chest images-relative score and several laboratory parameters to classify emergency room patients. Corona score accuracy was satisfactory, increasing the detection of positive patients' rate.

Keywords: COVID-19; Corona score; Emergency room; RT-PCR; laboratory markers.

PubMed Disclaimer

Conflict of interest statement

Potential conflict of interest: None declared.

References

    1. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical Features of Patients Infected With 2019 Novel Coronavirus in Wuhan, China. Lancet. 2020;395:497–506. 10.1016/S0140-6736(20)30183-5 - DOI - PMC - PubMed
    1. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020;323:1061–9. 10.1001/jama.2020.1585 - DOI - PMC - PubMed
    1. Benelli G, Buscarini E, Canetta C, La Piana G, Merli G, Scartabellati A, et al. SARS-COV-2 comorbidity network and outcome in hospitalized patients in Crema, Italy. Available at: https://www.medrxiv.org/content/10.1101/2020.04.14.20053090v2. Accessed June 9th 2020. https://doi.org/10.1101/2020.04.14.20053090 - DOI - DOI - PMC - PubMed
    1. Assandri R, Buscarini E, Canetta C, Scartabellati A, Viganò G, Montanelli A. Laboratory Biomarkers predicting COVID-19 severity in the Emergency room. Arch Med Res. 2020 May 21 [cited 2020 Jun 9]. [Epub ahead of print]. https://doi.org/10.1016/j.arcmed.2020.05.011 - DOI - PMC - PubMed
    1. Kurstjens S, van der Horst A, Herpers R, Geerits MWL, Kluiters-de Hingh YCM, Göttgens EL, et al. Rapid identification of SARS-CoV-2-infected patients at the emergency department using routine testing. Available at: https://www.medrxiv.org/content/10.1101/2020.04.20.20067512v1. Accessed June 9th 2020. https://doi.org/10.1101/2020.04.20.20067512 - DOI - DOI - PubMed

MeSH terms