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Review
. 2020 Jul 1;10(7):1993-2009.
eCollection 2020.

Early diagnosis and screening in lung cancer

Calin Cainap  1   2 , Laura A Pop  3 , Ovidiu Balacescu  4 , Simona S Cainap  5   6
Affiliations
Review

Early diagnosis and screening in lung cancer

Calin Cainap et al. Am J Cancer Res. .

Abstract

Lung cancer is the third most diagnosed cancer, but the first cause of cancer-related deaths worldwide. This rather high death rate is due mainly to the fact that most patients are diagnosed with advanced-stage cancer, for which the conventional treatment does not work. The most used screening method for lung cancer is a low-dose CT scan, but it is recommended for specific age populations and it also started different debates on its advantages for lung cancer diagnosis. Over the year, several new techniques have been developed that are less invasive, have lower side effect, and can be implemented at all types of populations. This article aimed to present the advantages and disadvantages of using several methods for lung cancer diagnosis, including analysis of volatile organic compounds, exhaled breath condensate analysis and specific genomic approaches.

Keywords: Lung cancer; early diagnosis; exhaled breath condensate; genomic approaches; volatile organic compounds.

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Conflict of interest statement

None.

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