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Review
. 2020 Sep;85(9):2635-2644.
doi: 10.1111/1750-3841.15360. Epub 2020 Aug 10.

Can food processing produce hypoallergenic egg?

Xiaojuan Ma  1 , Rui Liang  1 , Qianlu Xing  2 , Daniel Lozano-Ojalvo  3
Affiliations
Review

Can food processing produce hypoallergenic egg?

Xiaojuan Ma et al. J Food Sci. 2020 Sep.

Abstract

Eggs and their derived products are common foods that can induce food allergic reaction, especially in children. The reported incidence of egg allergy is 1% to 2%, and its prevalence has rapidly increased in recent years. Currently, there is no approved treatment for it. The clinical guidance for this adverse food reaction is the complete elimination of egg (and their derived products) from diet, which is difficult due to the wide use of egg ingredients in food industry. Food processing methods can affect the conformational and/or linear epitopes of allergens and may change the allergenicity of egg. Thermal treatment and various other processing methods based on the enzymatic hydrolysis and irradiation have been found useful in reducing allergenicity of certain egg allergens. However, processed egg proteins can also show an increased allergenicity after treatment and the correct pattern to follow for the generation of hypoallergenic products remains unclear. This review explores the influence of processing methods on egg allergenicity and reports the best options for the generation of hypoallergenic egg products to date.

Keywords: allergen; allergenicity; egg; processing.

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References

REFERENCES

    1. Acero-Lopez, A., Ullah, A., Offengenden, M., Jung, S., & Wu, J. (2012). Effect of high pressure treatment on ovotransferrin. Food Chemistry, 135(4), 2245-2252. https://doi.org/10.1016/j.foodchem.2012.07.071
    1. Amo, A., Rodríguez-Pérez, R., Blanco, J., Villota, J., Juste, S., Moneo, I., & Caballero, M. L. (2010). Gal d 6 is the second allergen characterized from egg yolk. Journal of Agricultural and Food Chemistry, 58(12), 7453-7457. https://doi.org/10.1021/jf101403h.
    1. Anyushin, A., Sap, A., Quanten, T., Proost, P., & Parac-Vogt, T. N. (2018). Selective hydrolysis of ovalbumin promoted by Hf(IV)-substituted Wells-Dawson-type polyoxometalate. Frontiers in Chemistry, 6, 614. https://doi.org/10.3389/fchem.2018.00614
    1. Arita, K., Babiker, E. E., Azakami, H., & Kato, A. (2001). Effect of chemical and genetic attachment of polysaccharides to proteins on the production of IgG and IgE. Journal of Agricultural and Food Chemistry, 49(4), 2030-2036. https://doi.org/10.1021/jf001120t
    1. Bai, L., Qiao, M., Zheng, R., Deng, C., Mei, S., & Chen, W. (2016). Phylogenomic analysis of transferrin family from animals and plants. Comparative Biochemistry and Physiology, Part D, 17, 1-8. https://doi.org/10.1016/j.cbd.2015.11.002

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