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. 2020 Oct;20(10):587-588.
doi: 10.1038/s41577-020-00421-x.

After 62 years of regulating immunity, dexamethasone meets COVID-19

Derek W Cain  1 , John A Cidlowski  2
Affiliations

After 62 years of regulating immunity, dexamethasone meets COVID-19

Derek W Cain et al. Nat Rev Immunol. 2020 Oct.

Abstract

Six months into the COVID-19 pandemic, effective treatments have been frustratingly sparse. The RECOVERY clinical trial, however, revealed that treatment with dexamethasone, a classic synthetic glucocorticoid, enhanced survival of critically ill patients with COVID-19. In this Comment, we discuss the immunological impacts of glucocorticoid therapy for COVID-19.

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Conflict of interest statement

The authors declare no competing interests.

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