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Review
. 2020 Oct;39(10):1038-1049.
doi: 10.1016/j.healun.2020.07.007. Epub 2020 Jul 23.

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Twenty-third pediatric lung transplantation report - 2020; focus on deceased donor characteristics

Don Hayes Jr  1 , Michael O Harhay  1 , Wida S Cherikh  1 , Daniel C Chambers  1 , Kiran K Khush  1 , Eileen Hsich  1 , Luciano Potena  1 , Aparna Sadavarte  1 , Tajinder P Singh  1 , Andreas Zuckermann  1 , Josef Stehlik  2 ; International Society for Heart and Lung Transplantation  1
Affiliations
Review

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Twenty-third pediatric lung transplantation report - 2020; focus on deceased donor characteristics

Don Hayes Jr et al. J Heart Lung Transplant. 2020 Oct.
No abstract available

Keywords: lung transplantation; organ donor; outcomes; pediatric; survival.

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Figures

Figure 1
Figure 1
Median donor (a) age (years), (b) BMI (kg/m2), and (c) PO2 (mm Hg) by year and geographic location (transplantations: January 1992–June 2018). BMI, body mass index; PO2, partial pressure of oxygen.
Figure 2
Figure 2
Donor sex distribution by geographic location and era (transplantations: January 1992–June 2018).
Figure 3
Figure 3
Donor cause of death distribution by geographic location and era (transplantations: January 1992–June 2018). CVA, cerebrovascular accident.
Figure 4
Figure 4
Percentage of donors with a history of (a) smoking and (b) alcohol use—for recipients aged 11–17 years and donors aged ≥11 years—by year (transplantations: January 2005–June 2018).
Figure 5
Figure 5
Kaplan–Meier survival within 12 months by donor age (transplantations: January 2000–June 2017). NS, non-significant.
Figure 6
Figure 6
Kaplan–Meier survival within 12 months by donor and recipient ages (transplantations: January 2000–June 2017). NS, non significant.
Figure 7
Figure 7
Kaplan–Meier survival within 12 months by donor age and geographic location (transplantations: January 2000–June 2017). NS, non-significant.
Figure 8
Figure 8
Kaplan–Meier survival within 12 months by (a) donor cause of death (transplants: January 2000–June 2017) and (b) donor PO2 (transplantations: January 2005–June 2017). CVA, cerebrovascular accident; NS, non-significant; PO2, partial pressure of oxygen.
Figure 9
Figure 9
Kaplan–Meier survival within 12 months for recipients aged 11—17 years and donors aged ≥11 years by donor history of smoking (transplantations: January 2000–June 2017). NS, nonsignificant.
Figure 10
Figure 10
Kaplan–Meier survival within 12 months by ischemic time (transplantations: January 2000–June 2017).
Figure 11
Figure 11
Kaplan–Meier survival within 12 months by ischemic time and donor age (transplantations: January 2000–June 2017). NS, non-significant.
Figure 12
Figure 12
Kaplan–Meier survival within 12 months by donor PO2 and ischemic time (transplantations: January 2005–June 2017). NS, non-significant; PO2, partial pressure of oxygen.
Figure 13
Figure 13
Kaplan–Meier survival within 5 years conditional on survival to 1 year by donor age (transplantations: January 2000–June 2013).
Figure 14
Figure 14
Kaplan–Meier survival within 5 years conditional on survival to 1 year by the recipient and donor ages (transplantations: January 2000–June 2013). NS, non-significant.
Figure 15
Figure 15
Kaplan–Meier survival within 5 years conditional on survival to 1 year by geographic location and donor age (transplantations: January 2000–June 2013). NS, non-significant. Note: There was no sufficient number of transplantations from donors 0 to 10 in other location.
Figure 16
Figure 16
Kaplan–Meier survival within 5 years conditional on survival to 1 year by (a) donor cause of death (transplantations: January 2000–June 2013) and (b) donor PO2 (transplantations: January 2005–June 2013). CVA, cerebrovascular accident; NS, non-significant; PO2, partial pressure of oxygen.
Figure 17
Figure 17
Kaplan–Meier survival within 5 years conditional on survival to 1 year by ischemic time (transplantations: January 2000–June 2013).
Figure 18
Figure 18
Kaplan–Meier survival within 5 years conditional on survival to 1 year by ischemic time and donor age (transplantations: January 2000–June 2013). NS, non-significant.
Figure 19
Figure 19
Freedom from BOS conditional on survival to discharge by donor age (transplantations: January 2000–June 2017). BOS, bronchiolitis obliterans syndrome; NS, non-significant.
Figure 20
Figure 20
Freedom from BOS conditional on survival to discharge by (a) donor cause of death (transplantations: January 2000–June 2017) and (b) donor PO2 (transplantations: January 2005–June 2017). BOS, bronchiolitis obliterans syndrome; CVA, cerebrovascular accident; NS, non-significant; PO2, partial pressure of oxygen.
Figure 21
Figure 21
Freedom from BOS conditional on survival to discharge by ischemic time (transplantations: January 2000–June 2017). BOS, bronchiolitis obliterans syndrome; NS, non-significant.
See this image and copyright information in PMC

References

    1. Hayes D Jr, Cherikh WS, Chambers DC, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: twenty-second pediatric lung and heart-lung transplantation report-2019; focus theme: donor and recipient size match. J Heart Lung Transplant 2019;38:1015–27. - PMC - PubMed
    1. Chambers DC, Cherikh WS, Harhay MO, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult lung and heart-lung transplantation report-2019; focus theme: donor and recipient size match. J Heart Lung Transplant 2019;38:1042–55. - PMC - PubMed
    1. Khush KK, Cherikh WS, Chambers DC, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult heart transplantation report - 2019; focus theme: donor and recipient size match [published correction appears in J Heart Lung Transplant 2020;39:91]. J Heart Lung Transplant 2019;38:1056–66. - PMC - PubMed
    1. Rossano JW, Singh TP, Cherikh WS, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: twenty-second pediatric heart transplantation report - 2019; focus theme: donor and recipient size match. J Heart Lung Transplant 2019;38:1028–41. - PMC - PubMed
    1. Yusen RD, Edwards LB, Kucheryavaya AY, et al. The registry of the International Society for Heart and Lung Transplantation: thirty-first adult lung and heart-lung transplant report–2014; focus theme: retransplantation. J Heart Lung Transplant 2014;33: 1009–24. - PubMed

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