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Case Reports
. 2020 Jul 1;13(7):1760-1765.
eCollection 2020.

B-lymphoblastic lymphoma with renal lesions as first symptom in a child: a case report and review of literature

Maojiang Yang  1 , Xian Qiong  2 , Yue Xiang  1 , Jianhao Liu  1 , Bing Li  1 , Chuan Zhang  1 , Sushant Kumar Das  1 , Xiaoxue Xu  1 , Hanfeng Yang  1
Affiliations
Case Reports

B-lymphoblastic lymphoma with renal lesions as first symptom in a child: a case report and review of literature

Maojiang Yang et al. Int J Clin Exp Pathol. .

Abstract

Lymphoblastic lymphoma (LBL) is a type of non Hodgkin's lymphoma. It is highly malignant and aggressive. Most patients have poor prognosis. Extramedullary involvement of B-LBL is very common, and the most vulnerable tissues are skin, bone, and soft tissues. Primary renal B-LBL is rarely reported. In this article, we report an 8-year-old boy who was admitted to hospital due to abdominal pain and vomiting. He was diagnosed with B lymphoblastoma by CT guided renal biopsy and bone marrow puncture. We review the clinical characteristics and diagnosis and treatment process of this case.

Keywords: Non-Hodgkin’s lymphoma; kidney; lymphoblastic lymphoma.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Ultrasound showed bilateral renal morphologic abnormalities, Echogenicicty was less homogeneous, and fluid necrosis was visible on the right.
Figure 2
Figure 2
A-E: Enhanced CT scanning showed a large irregular mass in the right kidney and multiple nodules in the left kidney. The plain scan showed a soft tissue mass with flaky necrosis. In the cortical, medullary, and delayed phases, the solid portion of the lesion was slightly strengthened. F: CT-guided percutaneous biopsy to obtain pathologic specimens.
Figure 3
Figure 3
Histopathology of right kidney: A. Nucleated small cells in fibrous tissue and striated muscle tissue under “right kidney” puncture tissue (H&E). B-D. Positivity for TDT, CD79a and CD99. E. About 90% of the neoplastic cells display nuclear Ki-67 staining.
See this image and copyright information in PMC

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