Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Sep;76(3):662-664.
doi: 10.1161/HYPERTENSIONAHA.120.14419. Epub 2020 Aug 12.

Segmental Adrenal Vein Sampling in Patients With Primary Aldosteronism: Superlative or Superfluous?

Adina F Turcu  1 , Celso E Gomez-Sanchez  2   3
Affiliations
Editorial

Segmental Adrenal Vein Sampling in Patients With Primary Aldosteronism: Superlative or Superfluous?

Adina F Turcu et al. Hypertension. 2020 Sep.
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Hypothetical case of primary aldosteronism undergoing segmental adrenal vein sampling (sAVS). Based on the criterion proposed by Kitamoto et al of plasma aldosterone >1400 ng/dl, sAVS would localize the aldosterone producing adenoma (APA) in the right inferior adrenal pole. Multiple additional sources of autonomous aldosterone production might be present in both adrenal glands, such as aldosterone-producing cell clusters (APCC) or micronodules, which would remain undiagnosed with sAVS and could cause residual PA following partial adrenalectomy.
See this image and copyright information in PMC

Comment on

References

    1. Rossitto G, Amar L, Azizi M, Riester A, Reincke M, Degenhart C, Widimsky J, Naruse M, Deinum J, Schultzekool L, Kocjan T, Negro A, Rossi E, Kline G, Tanabe A, Satoh F, Rump LC, Vonend O, Willenberg HS, Fuller P, Yang J, Nian Chee NY, Magill SB, Shafigullina Z, Quinkler M, Oliveras A, Chang CC, Wu VC, Somloova Z, Maiolino G, Barbiero G, Battistel M, Lenzini L, Quaia E, Pessina AC and Rossi GP. Subtyping of Primary Aldosteronism in the AVIS-2 Study: Assessment of Selectivity and Lateralization. The Journal of clinical endocrinology and metabolism. 2020;105. - PubMed
    1. Gomez-Sanchez CE, Qi X, Velarde-Miranda C, Plonczynski MW, Parker CR, Rainey W, Satoh F, Maekawa T, Nakamura Y, Sasano H and Gomez-Sanchez EP. Development of monoclonal antibodies against human CYP11B1 and CYP11B2. Molecular and cellular endocrinology. 2014;383:111–7. - PMC - PubMed
    1. De Sousa K, Boulkroun S, Baron S, Nanba K, Wack M, Rainey WE, Rocha A, Giscos-Douriez I, Meatchi T, Amar L, Travers S, Fernandes-Rosa FL and Zennaro MC. Genetic, Cellular and Molecular Heterogeneity in Adrenals with Aldosterone Producing Adenoma. Hypertension. 2020;in press. - PMC - PubMed
    1. Omata K, Satoh F, Morimoto R, Ito S, Yamazaki Y, Nakamura Y, Anand SK, Guo Z, Stowasser M, Sasano H, Tomlins SA and Rainey WE. Cellular and Genetic Causes of Idiopathic Hyperaldosteronism. Hypertension. 2018;72:874–880. - PMC - PubMed
    1. Sukor N, Gordon RD, Ku YK, Jones M and Stowasser M. Role of unilateral adrenalectomy in bilateral primary aldosteronism: a 22-year single center experience. The Journal of clinical endocrinology and metabolism. 2009;94:2437–45. - PubMed

Publication types