Limitations of Registration Trials for Nosocomial Pneumonia

Affiliations

¹ Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, Missouri, USA.
² Department of Pharmacy Practice, St Louis College of Pharmacy, St Louis, Missouri, USA.

Comment

Marin H Kollef et al. Clin Infect Dis. 2021.

. 2021 Dec 6;73(11):e4549-e4551.

doi: 10.1093/cid/ciaa926.

¹ Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, Missouri, USA.
² Department of Pharmacy Practice, St Louis College of Pharmacy, St Louis, Missouri, USA.

No abstract available

Keywords: antibiotics; pneumonia; ventilator-associated bacterial pneumonia.

Comment on

A Randomized, Double-blind, Multicenter Trial Comparing Efficacy and Safety of Imipenem/Cilastatin/Relebactam Versus Piperacillin/Tazobactam in Adults With Hospital-acquired or Ventilator-associated Bacterial Pneumonia (RESTORE-IMI 2 Study).
Titov I, Wunderink RG, Roquilly A, Rodríguez Gonzalez D, David-Wang A, Boucher HW, Kaye KS, Losada MC, Du J, Tipping R, Rizk ML, Patel M, Brown ML, Young K, Kartsonis NA, Butterton JR, Paschke A, Chen LF. Titov I, et al. Clin Infect Dis. 2021 Dec 6;73(11):e4539-e4548. doi: 10.1093/cid/ciaa803. Clin Infect Dis. 2021. PMID: 32785589 Free PMC article. Clinical Trial.