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. 2020 Jul 21;7(8):001811.
doi: 10.12890/2020_001811. eCollection 2020.

Non-Bacterial Thrombotic Endocarditis: A Presentation of COVID-19

Dilan Balata  1 , Johan Mellergård  2 , David Ekqvist  3 , Jacek Baranowski  4 , Isidro Albert Garcia  5 , Marina Volosyraki  6 , Mats Broqvist  1
Affiliations

Non-Bacterial Thrombotic Endocarditis: A Presentation of COVID-19

Dilan Balata et al. Eur J Case Rep Intern Med. .

Abstract

The SARS-CoV-2 virus is a newly emergent pathogen first identified in Wuhan, China, and responsible for the COVID-19 global pandemic. In this case report we describe a manifestation of non-bacterial thrombotic endocarditis with continuous peripheral embolization in a COVID-19-positive patient. The patient responded well to high-dose LMWH treatment with cessation of the embolic process.

Learning points: Raising awareness of possible complications of COVID-19.To highlight the importance of the careful consideration of and dosage of anticoagulation in non-bacterial thrombotic endocarditis.

Keywords: COVID-19; Endocarditis; mitral valve; ultrasound.

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Conflict of interest statement

Conflicts of Interests: The Authors declare that there are no competing interests.

Figures

Figure 1
Figure 1
Brain MRI. (a) Diffusion weighted images (DWI; b=1000) and (b) ADC maps recorded with a 3 Tesla scanner on admission day demonstrated widespread bilateral embolic infarctions supra- and infratentorially
Figure 2
Figure 2
Trans-esophageal echography revealed two vegetations on the mitral valve, one measuring 6×7mm and situated basally adjacent to the anterolateral commissure (marked with an arrow)
Figure 3
Figure 3
A full body F-18 FDG PET scan following the endocarditis protocol showed unspecific areas of increased uptake in the retroperitoneum (marked with an arrow) without enlarged lymph nodes in the area, thought to be caused by lumbar vein embolization. No signs of malignancy or obvious foci of infection were observed
See this image and copyright information in PMC

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