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. 2020 Aug 3;3(8):e2017708.
doi: 10.1001/jamanetworkopen.2020.17708.

Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19

Frank L van de Veerdonk  1   2 , Ilse J E Kouijzer  1   2 , Aline H de Nooijer  1 , Hans G van der Hoeven  3 , Coen Maas  4 , Mihai G Netea  1   2   5 , Roger J M Brüggemann  2   6
Affiliations

Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19

Frank L van de Veerdonk et al. JAMA Netw Open. .

Abstract

This case-control study examines the association between receipt of the bradykinin 2 (B2) receptor antagonist icatibant and improved oxygenation in patients with coronavirus disease 2019 (COVID-19).

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Netea reported serving as scientific founder for TTxD outside the submitted work. No other disclosures were reported.

Figures

Figure.
Figure.. Changes in Oxygen Supplementation at Baseline and 24 Hours in Individual Patients and Controls
Oxygen supplementation in individual patients (n = 9) and matched controls (n = 18).
See this image and copyright information in PMC

References

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