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Case Reports
. 1988 Feb;64(1):25-9.
doi: 10.1136/sti.64.1.25.

Managing trichomonal vaginitis refractory to conventional treatment with metronidazole

I H Ahmed-Jushuf  1 , A E Murray, J McKeown
Affiliations
Case Reports

Managing trichomonal vaginitis refractory to conventional treatment with metronidazole

I H Ahmed-Jushuf et al. Genitourin Med. 1988 Feb.

Abstract

Three patients with vulvovaginitis caused by Trichomonas vaginalis, which was refractory to conventional treatment with metronidazole are described. The T vaginalis strain isolated from one patient was resistant to metronidazole (minimum inhibitory concentration (MIC) more than 100 mg/l) under aerobic conditions, although under anaerobic conditions it was as susceptible as a normal reference strain. The effect of the concomitant use of other medication and the influence of other vaginal pathogens on the efficacy of metronidazole are highlighted.

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References

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