Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jul 24:11:745.
doi: 10.3389/fneur.2020.00745. eCollection 2020.

The Consequences of Coronavirus-Induced Cytokine Storm Are Associated With Neurological Diseases, Which May Be Preventable

Affiliations

The Consequences of Coronavirus-Induced Cytokine Storm Are Associated With Neurological Diseases, Which May Be Preventable

Ole Isacson. Front Neurol. .
No abstract available

Keywords: COVID-19; Parkinson's disease (PD); SARS-CoV-2; interleukin-1 receptor antagonist (IL-1 ra); pandemic; toll-like receptors; viral infection.

PubMed Disclaimer

References

    1. Deleidi M, Isacson O. Viral and inflammatory triggers of neurodegenerative diseases. Science Transl Med. (2012) 4:121ps123. 10.1126/scitranslmed.3003492 - DOI - PMC - PubMed
    1. Hallett PJ, Engelender S, Isacson O. Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease. J Neuroinflammation. (2019) 16:153. 10.1186/s12974-019-1532-2 - DOI - PMC - PubMed
    1. Koprich JB, Reske-Nielsen C, Mithal P, Isacson O. Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease. J Neuroinflammation. (2008) 5:8. 10.1186/1742-2094-5-8 - DOI - PMC - PubMed
    1. Deleidi M, Hallett PJ, Koprich JB, Chung CY, Isacson O. The Toll-like receptor-3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration. J Neurosci. (2010) 30:16091–101. 10.1523/JNEUROSCI.2400-10.2010 - DOI - PMC - PubMed
    1. Jang H, Boltz D, McClaren J, Pani AK, Smeyne M, Korff A, et al. . Inflammatory effects of highly pathogenic H5N1 influenza virus infection in the CNS of mice. J Neurosci. (2012) 32:1545–59. 10.1523/JNEUROSCI.5123-11.2012 - DOI - PMC - PubMed