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Review
. 2020 Nov:88:106885.
doi: 10.1016/j.intimp.2020.106885. Epub 2020 Aug 8.

Coronavirus disease 2019 (COVID-19): Immunological approaches and emerging pharmacologic treatments

Pedram Goodarzi  1 , Farzad Mahdavi  2 , Rasoul Mirzaei  3 , Hamze Hasanvand  4 , Mohammad Sholeh  5 , Farhad Zamani  6 , Masodreza Sohrabi  6 , Alireza Tabibzadeh  7 , Ali Salimi Jeda  7 , Mohammad Hadi Karbalaie Niya  6 , Hossein Keyvani  8 , Sajad Karampoor  9
Affiliations
Review

Coronavirus disease 2019 (COVID-19): Immunological approaches and emerging pharmacologic treatments

Pedram Goodarzi et al. Int Immunopharmacol. 2020 Nov.

Abstract

The SARS-CoV-2 virus is an etiological agent of pandemic COVID-19, which spreads rapidly worldwide. No proven effective therapies currently exist for this virus, and efforts to develop antiviral strategies for the treatment of COVID-19 are underway. The rapidly increasing understanding of SARS-CoV-2 virology provides a notable number of possible immunological procedures and drug targets. However, gaps remain in our understanding of the pathogenesis of COVID-19. In this review, we describe the latest information in the context of immunological approaches and emerging current antiviral strategies for COVID-19 treatment.

Keywords: Antiviral strategies; COVID-19; Drug targets; Immunological approaches; SARS-CoV-2.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Schematic represents the action of the mechanisms of candidates' drugs for treatments COVID-19.
See this image and copyright information in PMC

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