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Comment
. 2020 Dec;183(6):1152-1153.
doi: 10.1111/bjd.19489. Epub 2020 Sep 24.

Chilblains and COVID-19: why SARS-CoV-2 endothelial infection is questioned

M Baeck  1 , D Hoton  2 , L Marot  1   2 , A Herman  1
Affiliations
Comment

Chilblains and COVID-19: why SARS-CoV-2 endothelial infection is questioned

M Baeck et al. Br J Dermatol. 2020 Dec.

Abstract

Linked Article: Colmenero et al. Br J Dermatol 2020; 183:729–737.

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Figures

Figure 1
Figure 1
Immunohistochemistry for SARS‐CoV‐2 [using anti‐SARS‐CoV‐2 NP Antibody (Clone# 6F10) BioVision, Inc. Milpitas, CA, USA]. (a) Surgical pulmonary resection specimen of a patient without COVID‐19 who underwent thoracic surgery in 2019 before the COVID‐19 pandemic (original magnification × 20). (b) Autopsy pulmonary specimen of a patient with critical COVID‐19 (original magnification × 20). Diffuse endothelial staining of pulmonary vessels can be observed in both cases. (c) Skin biopsy specimens of chilblain lesions during the COVID‐19 pandemic (original magnification × 20). (d) Skin biopsy specimens of classical chilblains observed in 2015 prior to any cases of COVID‐19 (original magnification × 20). Diffuse endothelial staining of dermal vessels is present in both cases.
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References

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