Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Sep;140(9):1688-1690.
doi: 10.1016/j.jid.2020.03.946.

Standardizing Hidradenitis Suppurativa Skin Microbiome Research: The Methods Matter

Haley B Naik  1 , Vincent Piguet  2
Affiliations
Comment

Standardizing Hidradenitis Suppurativa Skin Microbiome Research: The Methods Matter

Haley B Naik et al. J Invest Dermatol. 2020 Sep.

Abstract

Cutaneous dysbiosis is implicated in hidradenitis suppurativa (HS) pathogenesis. Previous studies reveal skin microbiota shifts in HS lesional skin. In their report, Riverain-Gillet et al. (2020) extended these findings and reported skin microbiota shifts in unaffected HS skinfolds as well. Their study suggests that skin microbial shifts may precede clinical lesions and draws attention to study methods important for skin microbiome research.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST

HBN has received grant funding from AbbVie and consulting fees from 23andme and Johnson & Johnson. In addition, HBN is an unpaid board member of the Hidradenitis Suppurativa Foundation. VP undertakes advisory work for Pfizer, AbbVie, Janssen, UCB, Novartis, Almirall, and Celgene. VP has also received departmental support from AbbVie, Bausch Health, Celgene, Janssen, LEO Pharma, Lilly, NAOS, Novartis, Pfizer, Pierre-Fabre, and Sanofi.

Comment on

References

    1. Boer J, Weltevreden EF. Hidradenitis suppurativa or acne inversa. A clinicopathological study of early lesions. Br J Dermatol 1996;135:721–5. - PubMed
    1. Chakravorty S, Helb D, Burday M, Connell N, Alland D. A detailed analysis of 16S ribosomal RNA gene segments for the diagnosis of pathogenic bacteria. J Microbiol Methods 2007;69: 330–9. - PMC - PubMed
    1. Guet-Revillet H, Jais JP, Ungeheuer MN, Coignard-Biehler H, Duchatelet S, Delage M, et al. The microbiological landscape of anaerobic infections in hidradenitis suppurativa: a prospective metagenomic study. Clin Infect Dis 2017;65:282–91. - PubMed
    1. Ingram JR, Jenkins-Jones S, Knipe DW, Morgan CLI, Cannings-John R, Piguet V. Population-based clinical practice research datalink study using algorithm modelling to identify the true burden of hidradenitis suppurativa. Br J Dermatol 2018;178:917–24. - PubMed
    1. Kong HH, Andersson B, Clavel T, Common JE, Jackson SA, Olson ND, et al. Performing skin microbiome research: a method to the madness. J Invest Dermatol 2017;137: 561–8. - PMC - PubMed

Publication types

Substances