Clinical Trial
doi: 10.1111/j.1464-410x.1988.tb05062.x.
Flutamide versus stilboestrol in the management of advanced prostatic cancer. A controlled prospective study
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- PMID: 3280080
- DOI: 10.1111/j.1464-410x.1988.tb05062.x
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Clinical Trial
Flutamide versus stilboestrol in the management of advanced prostatic cancer. A controlled prospective study
Br J Urol.
1988 Feb.
Abstract
In a prospective randomised study the effect of flutamide 750 mg daily was compared with that of stilboestrol 3 mg daily in the treatment of 40 previously untreated patients with advanced prostatic cancer. There was a good subjective response to both treatments. After 12 months, a response was demonstrated in 13 of 20 patients treated with flutamide and 8 of 20 patients treated with stilboestrol. The difference was not statistically significant. Treatment with stilboestrol caused more frequent, and more severe, side effects than flutamide.
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