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Case Reports
. 2020 Sep;19(3):355-358.
doi: 10.1007/s12663-019-01273-2. Epub 2019 Aug 13.

Localized Oral Histoplasmosis in an Immunocompetent Patient: A Rare Occurrence with Review of the Literature

Arun Kumar  1 , Vidya Rattan  2 , Sachin Rai  2 , Kaniyappan Nambiyar  3
Affiliations
Case Reports

Localized Oral Histoplasmosis in an Immunocompetent Patient: A Rare Occurrence with Review of the Literature

Arun Kumar et al. J Maxillofac Oral Surg. 2020 Sep.
No abstract available

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Pre-treatment clinical photographs of the patient depicting ulcerative lesion with inflamed base and rolled out margins in 33–36 gingival region (3 cm × 1 cm) (a), shallow ulcerative lesion covered with psuedomembrane in 25–26 palatal region (0.5 cm × 0.5 cm) (b)
Fig. 2
Fig. 2
Histopathological examination of biopsy tissue showed ulcer with granulation tissue (H&E, 200×) (a), epitheloid cell granuloma with multinucleated giant cell containing H. Capsulatum (H&E, 1000×) (b), and sheets of yeast form of H. Capsulatum in the cytoplasm of histiocytes (H&E, 1000×) (c). PAS stain highlights the yeast form of the organism having crescent shaped nuclei (PAS, 1000×) (d)
Fig. 3
Fig. 3
Post-treatment clinical photographs (a, b) of the patient showed complete resolution of the oral lesions
See this image and copyright information in PMC

References

    1. Mignogna MD, Fedele S, Lo Russo L, Ruoppo E, Lo Muzio L. A case of oral localized histoplasmosis in an immunocompetent patient. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol. 2001;20:753–755. - PubMed
    1. Padhye AA, Pathak AA, Katkar VJ, Hazare VK, Kaufman L. Oral histoplasmosis in India: a case report and an overview of cases reported during 1968–1992. J Med Vet Mycol Bi-Mon Publ Int Soc Hum Anim Mycol. 1994;32:93–103. - PubMed
    1. Azar MM, Hage CA. Clinical perspectives in the diagnosis and management of histoplasmosis. Clin Chest Med. 2017;38:403–415. - PubMed
    1. Economopoulou P, Laskaris G, Kittas C. Oral histoplasmosis as an indicator of HIV infection. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 1998;86:203–206. - PubMed
    1. Ramachandran S, Balan A. Oral histoplasmosis—a case report and review. J Indian Acad Oral Med Radiol. 2007;1(19):300.

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