Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jul 27:13:179-185.
doi: 10.2147/IJNRD.S231142. eCollection 2020.

Current Knowledge of Vaccinations in Chronic Kidney Disease Patients

Affiliations
Review

Current Knowledge of Vaccinations in Chronic Kidney Disease Patients

Intissar Haddiya. Int J Nephrol Renovasc Dis. .

Abstract

Chronic kidney disease (CKD) patients are at high risk for infectious complications. This is partly due to their dysfunctional immune system, especially in advanced CKD stages. Vaccination represents an important prevention strategy in these patients, as several studies have reported lower infection rates and significantly reduced morbidity and mortality in hospitals adopting vaccination protocols. However, vaccination rates are particularly low in these patients, and the diminished immune responsiveness remains the main issue of vaccination in CKD patients. Besides, there are various immunization protocols across the world in the absence of optimal vaccination policies. This paper aims to discuss the current knowledge of vaccination in this immunocompromised group of patients based on recent evidence and recommendations.

Keywords: chronic kidney disease; dialysis; immune system; immunizations; kidney transplant; vaccines.

PubMed Disclaimer

Conflict of interest statement

The author reports no conflicts of interest in this work.

References

    1. Snigdha R, Chandrika C, Jerry Y. Vaccination in Chronic Kidney Disease. Adv Chronic Kidney Dis. 2019;26(1):72–78. doi:10.1053/j.ackd.2018.10.002 - DOI - PubMed
    1. Naqvi SB, Collins AJ. Infectious complications in Chronic Kidney Disease. Adv Chronic Kidney Dis. 2006;13(3):199–204. doi:10.1053/j.ackd.2006.04.004 - DOI - PubMed
    1. Kosmadakis G, Albaret J. Enrique Da Costa Correia, Frederic Somda, Didier Aguilera. Vaccination practices in dialysis patients: A narrative review. Semin Dial. 2018;1–12. - PubMed
    1. Lee Ventola C. Immunization in the United States: recommendations, barriers, and measures to improve compliance. part 2: adult vaccinations. Pharm Ther. 2016;41(8):P&T. - PMC - PubMed
    1. Annunziata K, Rak A, Del Buono H, et al. Vaccination rates among the general adult popula- tion and high-risk groups in the United States. PLoS One. 2012;7(11):e50553. doi:10.1371/journal.pone.0050553 - DOI - PMC - PubMed