Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Aug 1;10(4):507-512.
doi: 10.31661/jbpe.v0i0.2003-1080. eCollection 2020 Aug.

A Deep Learning Approach to Automatic Recognition of Arcus Senilis

Affiliations

A Deep Learning Approach to Automatic Recognition of Arcus Senilis

Amini N et al. J Biomed Phys Eng. .

Abstract

Background: Arcus Senilis (AS) appears as a white, grey or blue ring or arc in front of the periphery of the iris, and is a symptom of abnormally high cholesterol in patients under 50 years old.

Objective: This work proposes a deep learning approach to automatic recognition of AS in eye images.

Material and methods: In this analytical study, a dataset of 191 eye images (130 normal, 61 with AS) was employed where ¾ of the data were used for training the proposed model and ¼ of the data were used for test, using a 4-fold cross-validation. Due to the limited amount of training data, transfer learning was conducted with AlexNet as the pretrained network.

Results: The proposed model achieved an accuracy of 100% in classifying the eye images into normal and AS categories.

Conclusion: The excellent performance of the proposed model despite limited training set, demonstrate the efficacy of deep transfer learning in AS recognition in eye images. The proposed approach is preferred to previous methods for AS recognition, as it eliminates cumbersome segmentation and feature engineering processes.

Keywords: Arcus Senilis; Classification; Deep Learning; Transfer Learning.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None

Figures

Figure 1
Figure 1
Samples of eye images (a) normal, (b) Arcus Senilis (AS)
Figure 2
Figure 2
The block diagram of the proposed method: AlexNet (with replaced three last layers) is first trained with data from 3 folds and then the trained model is tested on data from the remaining fold.
Figure 3
Figure 3
The proposed model loss function for the test set, during the training progress.
Figure 4
Figure 4
The confusion matrix of the proposed model for one fold.

References

    1. Ramlee R A, Aziz K A, Ranjit S, Esro M. Automated detecting arcus senilis, symptom for cholesterol presence using iris recognition algorithm. Journal of Telecommunication, Electronic and Computer Engineering (JTEC) 2011;3(2):29–39.
    1. Berggren L. Iridology: A critical reveiw. Acta Ophthalmologica. 1985;63(1):1–8. doi: 10.1111/j.1755-3768.1985.tb05205.x. - DOI
    1. Morrison P J. The iris–a window into the genetics of common and rare eye diseases. The Ulster medical journal. 2010;79(1):3–5. [ PMC Free Article ] - PMC - PubMed
    1. Anjarsari A, Damayanti A, Pratiwi A B, Winarko E. Hybrid radial basis function with firefly algorithm and simulated annealing for detection of high cholesterol through iris images. IOP Conf Ser: Mater Sci Eng; Malang, Indonesia: IOP Publishing Ltd; 2019 . - DOI
    1. Um J Y, An N H, Yang G B, Lee G M, Cho J J, Cho J W, Hwang W J, et al. Novel approach of molecular genetic understanding of iridology: relationship between iris constitution and angiotensin converting enzyme gene polymorphism. The American journal of Chinese medicine. 2005;33(3):501–5. doi: 10.1142/S0192415X05003090. - DOI - PubMed