Current advances in the diagnosis and personalized treatment of breast cancer: lessons from tumor biology

Abstract

Breast cancer treatment has advanced enormously in the last decade. Most of this is due to advances reached in the knowledge regarding tumor biology, mainly in the field of diagnosis and treatment. This review brings information about how the genomics-based information contributed to advances in breast cancer diagnosis and prognosis perspective, as well as presents how tumor biology discoveries fostered the main therapeutic approaches available to treat such patients, based on a personalized point of view.

Keywords: biomarkers; breast cancer; genomic profile; immune checkpoints inhibitors; multigene arrays; personalized treatment; prognosis; therapy development; tumor biology.