Cytotoxic lesion of the corpus callosum as presenting neuroradiological manifestation of COVID-2019 infection

doi:10.1007/s00415-020-10166-1

. 2021 May;268(5):1595-1597.

doi: 10.1007/s00415-020-10166-1. Epub 2020 Aug 18.

Cytotoxic lesion of the corpus callosum as presenting neuroradiological manifestation of COVID-2019 infection

Géraud Forestier¹, Isaure de Beaurepaire², Grégoire Bornet², Grégoire Boulouis³

Affiliations

¹ Neuroradiology Department, University Hospital of Limoges, Dupuytren, 2 avenue Martin Luther King, 87042, Limoges Cedex, France. geraudforestier@gmail.com.
² Radiology Department, Hôpital Privé d'Antony, 25 Avenue de la Providence, 92160, Antony, France.
³ Neuroradiology Department, INSERM U1266, Université de Paris, Sainte-Anne Hospital, Paris, France.

PMID: 32809155
PMCID: PMC7433278
DOI: 10.1007/s00415-020-10166-1

Cytotoxic lesion of the corpus callosum as presenting neuroradiological manifestation of COVID-2019 infection

Géraud Forestier et al. J Neurol. 2021 May.

. 2021 May;268(5):1595-1597.

doi: 10.1007/s00415-020-10166-1. Epub 2020 Aug 18.

Authors

Géraud Forestier¹, Isaure de Beaurepaire², Grégoire Bornet², Grégoire Boulouis³

Affiliations

¹ Neuroradiology Department, University Hospital of Limoges, Dupuytren, 2 avenue Martin Luther King, 87042, Limoges Cedex, France. geraudforestier@gmail.com.
² Radiology Department, Hôpital Privé d'Antony, 25 Avenue de la Providence, 92160, Antony, France.
³ Neuroradiology Department, INSERM U1266, Université de Paris, Sainte-Anne Hospital, Paris, France.

PMID: 32809155
PMCID: PMC7433278
DOI: 10.1007/s00415-020-10166-1

No abstract available

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Conflict of interest statement

All authors report no disclosures.

Figures

**Fig. 1**
Axial brain MRI images demonstrate increased diffusion weighted signal in the splenium of the corpus callosum (left), confirmed as low signal on the ADC map (right)

**Fig. 2**
Chest CT-scan demonstrates ground glass opacities in the left lower pulmonary lobe (left) and repeat CT-scan (right) showing bilateral pulmonary lesions with crazy-paving pattern

See this image and copyright information in PMC

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References

1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed
1. Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020 doi: 10.1001/jama.2020.1585. - DOI - PMC - PubMed
1. Zhou Z, Guo D, Li C, et al. Coronavirus disease 2019: initial chest CT findings. Eur Radiol. 2020 doi: 10.1007/s00330-020-06816-7. - DOI - PMC - PubMed
1. WHO (2020) Coronavirus disease 2019 (COVID-19) https://www.who.int/emergencies/diseases/novel-coronavirus-2019
1. Desforges M, Le Coupanec A, Dubeau P, et al. Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system? Viruses. 2020;12:14. doi: 10.3390/v12010014. - DOI - PMC - PubMed

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[1] Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed

[2] Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed

[3] Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020 doi: 10.1001/jama.2020.1585. - DOI - PMC - PubMed

[4] Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020 doi: 10.1001/jama.2020.1585. - DOI - PMC - PubMed

[5] Zhou Z, Guo D, Li C, et al. Coronavirus disease 2019: initial chest CT findings. Eur Radiol. 2020 doi: 10.1007/s00330-020-06816-7. - DOI - PMC - PubMed

[6] Zhou Z, Guo D, Li C, et al. Coronavirus disease 2019: initial chest CT findings. Eur Radiol. 2020 doi: 10.1007/s00330-020-06816-7. - DOI - PMC - PubMed

[7] WHO (2020) Coronavirus disease 2019 (COVID-19) https://www.who.int/emergencies/diseases/novel-coronavirus-2019

[8] WHO (2020) Coronavirus disease 2019 (COVID-19) https://www.who.int/emergencies/diseases/novel-coronavirus-2019

[9] Desforges M, Le Coupanec A, Dubeau P, et al. Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system? Viruses. 2020;12:14. doi: 10.3390/v12010014. - DOI - PMC - PubMed

[10] Desforges M, Le Coupanec A, Dubeau P, et al. Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system? Viruses. 2020;12:14. doi: 10.3390/v12010014. - DOI - PMC - PubMed

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Cytotoxic lesion of the corpus callosum as presenting neuroradiological manifestation of COVID-2019 infection

Affiliations

Cytotoxic lesion of the corpus callosum as presenting neuroradiological manifestation of COVID-2019 infection

Authors

Affiliations

Conflict of interest statement

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