[Dietary modification of bile lipids]
- PMID: 3280933
[Dietary modification of bile lipids]
Abstract
The average incidence of gallstones in european countries is about 25%. Excessive secretion of cholesterol into the bile can predispose to saturation and gallstone-formation. Obesity, overnutrition, diets rich in refined carbohydrates, diets high in cholesterol intake and poor in dietary fibre, lipid lowering drugs, age and female sex hormones are recognized causing increased cholesterol secretion into the bile. These metabolic consequences may predispose to a higher incidence of cholesterol gallstone than in normal persons. Taking all the results of the literature together patients with gallstones should be encouraged to take a low cholesterol, low calorie, low refined carbohydrate and high polyunsaturated fat diet rich in bran und vegetable fibre. Obese patients should reduce their body weight. These dietary recommendations should be given for patients with gallstones during bile acid therapy and after successful dissolution in order to prevent gallstone recurrence.
Similar articles
-
Effects of dietary cholesterol on cholesterol and bile acid homeostasis in patients with cholesterol gallstones.J Clin Invest. 1994 Mar;93(3):1186-94. doi: 10.1172/JCI117072. J Clin Invest. 1994. PMID: 8132759 Free PMC article.
-
Interaction of chenodeoxycholic acid and dietary cholesterol in the treatment of cholesterol gallstones.Am J Surg. 1982 Jan;143(1):48-54. doi: 10.1016/0002-9610(82)90128-3. Am J Surg. 1982. PMID: 7053655
-
Dietary impact on biliary lipids and gallstones.Annu Rev Nutr. 1992;12:299-326. doi: 10.1146/annurev.nu.12.070192.001503. Annu Rev Nutr. 1992. PMID: 1503808 Review.
-
The effects of chenodiol on biliary lipids and their association with gallstone dissolution in the National Cooperative Gallstone Study (NCGS).J Clin Invest. 1984 Apr;73(4):1156-66. doi: 10.1172/JCI111301. J Clin Invest. 1984. PMID: 6368591 Free PMC article. Clinical Trial.
-
[Effect of hypolipidemic treatment on the composition of bile and the risk or cholesterol gallstone disease].Cas Lek Cesk. 2007;146(1):24-34. Cas Lek Cesk. 2007. PMID: 17310581 Review. Czech.
Cited by
-
Gallstone recurrence after successful dissolution therapy.Dig Dis Sci. 1996 Feb;41(2):235-41. doi: 10.1007/BF02093810. Dig Dis Sci. 1996. PMID: 8601364 Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical