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Book

Anetoderma

Jordan C. Cook  1 , Hasnain A. Syed  2 , Yana Puckett
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Anetoderma

Jordan C. Cook et al.
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Excerpt

The term "anetoderma" originates from the Greek words anetos (relaxed) and derma (skin). First described by Jadassohn in 1892, anetoderma is a benign disorder of elastolysis characterized by well-circumscribed, focal areas of flaccid skin. Clinically, these lesions appear as round to oval atrophic depressions, wrinkled macules, patches, or herniated sac-like protrusions surrounded by normal skin. The lesions may be skin-colored, white, gray, brown, or blue and can measure from millimeters to centimeters. Anetoderma most commonly affects the trunk and proximal extremities. Once present, the disease remains active for at least 15 years. Spontaneous regression has never been reported.

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Conflict of interest statement

Disclosure: Jordan Cook declares no relevant financial relationships with ineligible companies.

Disclosure: Hasnain Syed declares no relevant financial relationships with ineligible companies.

Disclosure: Yana Puckett declares no relevant financial relationships with ineligible companies.

References

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    1. de Faria Melo M, de Faria Melo I, Escobar GF. Secondary Anetoderma. JAMA Dermatol. 2021 Apr 14; - PubMed
    1. Barbosa J, João AL, João A, Fernandes C. Secondary Syphilis-Induced Anetoderma. Actas Dermosifiliogr. 2024 Sep;115(8):838-840. - PubMed
    1. Sparsa A, Piette JC, Wechsler B, Amoura Z, Francès C. Anetoderma and its prothrombotic abnormalities. J Am Acad Dermatol. 2003 Dec;49(6):1008-12. - PubMed

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