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Book

Minimal Change Disease

Glenda Zamora  1 , Anthony L. Pearson-Shaver  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Free Books & Documents
Book

Minimal Change Disease

Glenda Zamora et al.
Free Books & Documents

Excerpt

Minimal change disease (MCD) is one of the most common causes of idiopathic nephrotic syndrome in children. It accounts for 70% to 90% of children that present with nephrotic syndrome who are older than one year old as opposed to 10-15% of adults who present with nephrotic syndrome. Minimal change disease is distinctive for proteinuria that results in edema and intravascular volume depletion, with a good response to steroids. Minimal Change Disease has been labeled “minimal change lesion,” “nil disease,” and “lipoid nephrosis (a description of lipid droplets in urine seen on light microscopy). Minimal change disease has a particularly good prognosis in pediatric patients.

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Conflict of interest statement

Disclosure: Glenda Zamora declares no relevant financial relationships with ineligible companies.

Disclosure: Anthony Pearson-Shaver declares no relevant financial relationships with ineligible companies.

References

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