Adult Diabetic Ketoacidosis
- PMID: 32809558
- Bookshelf ID: NBK560723
Adult Diabetic Ketoacidosis
Excerpt
Diabetic ketoacidosis (DKA) represents a critical metabolic emergency marked by hyperglycemia, acidosis, and ketonemia. Although most frequently associated with type 1 diabetes, the condition can also affect individuals with type 2 diabetes under certain circumstances. The severity of DKA stems from its rapid onset and potential to cause significant morbidity and mortality if unrecognized or untreated.
The development of DKA commonly results from new-onset diabetes, underlying infections, or poor adherence to therapy. Additional stressors such as acute illness, trauma, or medication effects may also precipitate the condition. Early identification and prompt management remain essential, as timely intervention greatly improves patient outcomes.
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- Karslioglu French E, Donihi AC, Korytkowski MT. Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome: review of acute decompensated diabetes in adult patients. BMJ. 2019 May 29;365:l1114. - PubMed
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