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Book

Nasal Polyps

Edgar del Toro  1 , Frances Mei L. Hardin  2 , Juan Portela  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Nasal Polyps

Edgar del Toro et al.
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Excerpt

Nasal polyps are benign, inflammatory, and hyperplastic outgrowths of the sinonasal mucosa. These lesions most commonly manifest in patients who have chronic rhinosinusitis (CRS), which is why the term "chronic rhinosinusitis with nasal polyposis" (CRSwNP) is often used when discussing nasal polyps. These growths are also associated with other conditions, including aspirin-exacerbated respiratory disease (AERD), certain systemic vasculitides, and cystic fibrosis.

Polyposis represents an end-stage manifestation of poorly controlled allergies, with management of existing polyps only marking the beginning of treatment. Once polyps are addressed, local and systemic therapies targeting the underlying allergic etiology are crucial to prevent rapid recurrence. Symptoms range from asymptomatic to significant nasal obstruction, facial congestion, anosmia, ageusia, and rhinorrhea, all of which severely impair quality of life (QOL).

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Conflict of interest statement

Disclosure: Edgar del Toro declares no relevant financial relationships with ineligible companies.

Disclosure: Frances Mei Hardin declares no relevant financial relationships with ineligible companies.

Disclosure: Juan Portela declares no relevant financial relationships with ineligible companies.

References

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    1. Stevens WW, Schleimer RP, Kern RC. Chronic Rhinosinusitis with Nasal Polyps. J Allergy Clin Immunol Pract. 2016 Jul-Aug;4(4):565-72. - PMC - PubMed
    1. Ta NH. Will we ever cure nasal polyps? Ann R Coll Surg Engl. 2019 Jan;101(1):35-39. - PMC - PubMed
    1. Bhattacharyya N, Gilani S. Prevalence of Potential Adult Chronic Rhinosinusitis Symptoms in the United States. Otolaryngol Head Neck Surg. 2018 Sep;159(3):522-525. - PubMed
    1. Song WJ, Lee JH, Won HK, Bachert C. Chronic Rhinosinusitis with Nasal Polyps in Older Adults: Clinical Presentation, Pathophysiology, and Comorbidity. Curr Allergy Asthma Rep. 2019 Sep 05;19(10):46. - PubMed

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