Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Fibrosarcoma

Donald D. Davis  1 , Muhammad Taqi  2 , Steven M. Kane  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Fibrosarcoma

Donald D. Davis et al.
Free Books & Documents

Excerpt

Fibrosarcomas are defined as malignant neoplasms composed of fibroblasts that may have varying amounts of collagen production and a "herringbone" architecture. Depending upon the origin, there are 2 main categories of fibrosarcomas: bone and soft tissue tumors. Adult fibrosarcomas have displayed a declining incidence over the past several decades as the classification of fibrosarcoma continually narrows, and other mesenchymal and non-mesenchymal tumors that mimic fibrosarcomas are more accurately diagnosed. Fibrosarcomas can be subdivided into 2 types: infantile or congenital fibrosarcomas and adult-type fibrosarcomas. Infantile fibrosarcomas rarely metastasize, while adult-type fibrosarcomas are highly malignant.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Donald Davis declares no relevant financial relationships with ineligible companies.

Disclosure: Muhammad Taqi declares no relevant financial relationships with ineligible companies.

Disclosure: Steven Kane declares no relevant financial relationships with ineligible companies.

References

    1. Jo VY, Fletcher CD. WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition. Pathology. 2014 Feb;46(2):95-104. - PubMed
    1. Folpe AL. Fibrosarcoma: a review and update. Histopathology. 2014 Jan;64(1):12-25. - PubMed
    1. Augsburger D, Nelson PJ, Kalinski T, Udelnow A, Knösel T, Hofstetter M, Qin JW, Wang Y, Gupta AS, Bonifatius S, Li M, Bruns CJ, Zhao Y. Current diagnostics and treatment of fibrosarcoma -perspectives for future therapeutic targets and strategies. Oncotarget. 2017 Nov 28;8(61):104638-104653. - PMC - PubMed
    1. Angiero F, Rizzuti T, Crippa R, Stefani M. Fibrosarcoma of the jaws: two cases of primary tumors with intraosseous growth. Anticancer Res. 2007 Jul-Aug;27(4C):2573-81. - PubMed
    1. Bahrami A, Folpe AL. Adult-type fibrosarcoma: A reevaluation of 163 putative cases diagnosed at a single institution over a 48-year period. Am J Surg Pathol. 2010 Oct;34(10):1504-13. - PubMed

Publication types

LinkOut - more resources