Neurological Sequelae in Youngest Adult Behcet's Disease Patient on Infliximab

Abstract

Neuro-Behcet's disease is a rare neurological complication of Behcet's disease presenting between second and fourth decades of life. The etiology of Behcet's disease is still unknown but genetic predisposition has been described to play a role. The disease is reported more in males than females. Neurological involvement could cause brain parenchymal, vascular or meningeal changes with other distinct systemic symptoms, which may include orogenital ulcers, uveitis and skin lesions. Parenchymal neuro-Behcet's disease has a poor prognosis. MRI aids in diagnosing and differentiating it from other entities. Treatment includes anti-inflammatory drugs and immunotherapeutics. Our case is the youngest adult reported so far and is an unusual presentation of neuro-Behcet's disease, as the patient was already in remission and on infliximab infusion. Key Words: Neuro-Behcet's, MRI, Infliximab.