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Review
. 2020 Oct;39(10):1003-1015.
doi: 10.1016/j.healun.2020.07.010. Epub 2020 Jul 23.

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 37th adult heart transplantation report-2020; focus on deceased donor characteristics

Kiran K Khush  1 , Luciano Potena  1 , Wida S Cherikh  1 , Daniel C Chambers  1 , Michael O Harhay  1 , Don Hayes Jr  1 , Eileen Hsich  1 , Aparna Sadavarte  1 , Tajinder P Singh  1 , Andreas Zuckermann  1 , Josef Stehlik  2 ; International Society for Heart and Lung Transplantation  1
Affiliations
Review

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 37th adult heart transplantation report-2020; focus on deceased donor characteristics

Kiran K Khush et al. J Heart Lung Transplant. 2020 Oct.
No abstract available

Keywords: cardiac allograft vasculopathy; heart transplantation; organ donor; risk factors; survival.

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Figures

Figure 1
Figure 1
Median donor (a) age by year and geographic location (transplants: January 1992–June 2018) and (b) BMI by year and geographic location (transplants: January 1995–June 2018). BMI, body mass index.
Figure 2
Figure 2
Donor cause of death by geographic location and era (transplants: January 1992–June 2018). CVA, cerebrovascular accident.
Figure 3
Figure 3
Percentage of donors with a history of (a) smoking (transplants: January 1995–June 2018) and (b) alcohol use (transplants: January 2005–June 2018).
Figure 4
Figure 4
Percentage of donors with a history of cocaine and other drug use (transplants: January 2000–June 2018).
Figure 5
Figure 5
Percentage of donors with (a) diabetes and hypertension (transplants: January 1995–June 2018) and (b) LVEF <50% (transplants: January 2005–June 2018). LVEF, left ventricular ejection fraction.
Figure 6
Figure 6
Kaplan–Meier survival within 12 months by donor and recipient age (transplants: January 2000–June 2017).
Figure 7
Figure 7
Kaplan–Meier survival within 12 months by donor (a) cause of death (transplants: January 2000–June 2017) and (b) LVEF (transplants: January 2005–June 2017). CVA, cerebrovascular accident; LVEF, left ventricular ejection fraction.
Figure 8
Figure 8
Kaplan–Meier survival within 12 months by donor history of (a) smoking (transplants: January 2000–June 2017) and (b) alcohol use (transplants: January 2005–June 2017).
Figure 9
Figure 9
Kaplan–Meier survival within 12 months by allograft ischemic time and donor age (transplants: January 2000–June 2017).
Figure 10
Figure 10
Kaplan–Meier survival within 12 months by allograft ischemic time and donor LVEF (transplants: January 2005–June 2017). LVEF, left ventricular ejection fraction.
Figure 11
Figure 11
Kaplan–Meier survival within 5 years conditional on survival to 1 year by donor history of (a) diabetes (transplants: January 2000–June 2013) and (b) hypertension (transplants: January 2000–June 2013).
Figure 12
Figure 12
Kaplan–Meier survival within 5 years conditional on survival to 1 year by donor (a) cause of death (transplants: January 2000–June 2013) and (b) LVEF (transplants: January 2005–June 2013). CVA, cerebrovascular accident; LVEF, left ventricular ejection fraction; NS, non-significant.
Figure 13
Figure 13
Kaplan–Meier survival within 5 years conditional on survival to 1 year by allograft ischemic time and donor history of hypertension (transplants: January 2000–June 2013). NS, non-significant.
Figure 14
Figure 14
Kaplan–Meier freedom from CAV conditional on survival to discharge by donor age (transplants: January 2000–June 2017). CAV, cardiac allograft vasculopathy.
Figure 15
Figure 15
Kaplan–Meier freedom from CAV conditional on survival to discharge by donor (a) cause of death (transplants: January 2000–June 2017) and (b) LVEF (transplants: January 2005–June 2017). CAV, cardiac allograft vasculopathy; CVA, cerebrovascular accident; LVEF, left ventricular ejection fraction; NS, non-significant.
Figure 16
Figure 16
Kaplan–Meier freedom from CAV conditional on survival to discharge by donor history of (a) diabetes (transplants: January 2000–June 2017) and (b) hypertension (transplants: January 2000–June 2017). CAV, cardiac allograft vasculopathy.
Figure 17
Figure 17
Kaplan–Meier freedom from CAV conditional on survival to discharge by donor history of (a) smoking (transplants: January 2000–June 2017) and (b) alcohol use (transplants: January 2005–June 2017). CAV, cardiac allograft vasculopathy.
See this image and copyright information in PMC

References

    1. Khush KK. Donor selection in the modern era. Ann Cardiothorac Surg 2018;7:126–34. - PMC - PubMed
    1. Hsich EM. Matching the market for heart transplantation. Circ Heart Fail 2016;9:e002679. - PMC - PubMed
    1. Khush KK, Cherikh WS, Chambers DC, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult heart transplantation report - 2019; focus theme: donor and recipient size match [published correction appears in J Heart Lung Transplant 2020;39:91]. J Heart Lung Transplant 2019;38:1056–66. - PMC - PubMed
    1. Khush KK, Cherikh WS, Chambers DC, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-fifth adult heart transplantation report-2018; focus theme: multiorgan transplantation. J Heart Lung Transplant 2018;37:1155–68. - PubMed
    1. Lund LH, Khush KK, Cherikh WS, et al. The Registry of the International Society for Heart and Lung Transplantation: thirty-fourth adult heart transplantation report-2017; focus theme: allograft ischemic time. J Heart Lung Transplant 2017;36:1037–46. - PubMed

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