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Comment
. 2020 Nov;28(11):1481-1482.
doi: 10.1038/s41431-020-00709-5. Epub 2020 Aug 19.

Cancer surveillance for individuals with Li-Fraumeni syndrome

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Comment

Cancer surveillance for individuals with Li-Fraumeni syndrome

Christian P Kratz et al. Eur J Hum Genet. 2020 Nov.
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Comment in

  • Reply to Kratz et al.
    Frebourg T, Lagercrantz SB, Oliveira C, Magenheim R, Evans DG; European Reference Network GENTURIS. Frebourg T, et al. Eur J Hum Genet. 2020 Nov;28(11):1483-1485. doi: 10.1038/s41431-020-00710-y. Epub 2020 Aug 13. Eur J Hum Genet. 2020. PMID: 32792624 Free PMC article. No abstract available.

Comment on

References

    1. Frebourg T, Bajalica Lagercrantz S, Oliveira C, Magenheim R, Evans DG, European Reference Network G. Guidelines for the Li-Fraumeni and heritable TP53-related cancer syndromes. Eur J Hum Genet. 2020. 10.1038/s41431-020-0638-4. - PMC - PubMed
    1. Li FP, Fraumeni JF., Jr Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome? Ann Intern Med. 1969;71:747–52. doi: 10.7326/0003-4819-71-4-747. - DOI - PubMed
    1. Rana HQ, Gelman R, LaDuca H, McFarland R, Dalton E, Thompson J, et al. Differences in TP53 mutation carrier phenotypes emerge from panel-based testing. J Natl Cancer Inst. 2018;110:863–70.. doi: 10.1093/jnci/djy001. - DOI - PubMed
    1. Grobner SN, Worst BC, Weischenfeldt J, Buchhalter I, Kleinheinz K, Rudneva VA, et al. The landscape of genomic alterations across childhood cancers. Nature. 2018;555:321–7. doi: 10.1038/nature25480. - DOI - PubMed
    1. Sabapathy K, Lane DP. Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others. Nat Rev Clin Oncol. 2018;15:13–30. doi: 10.1038/nrclinonc.2017.151. - DOI - PubMed

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