The antibiotic paradox: why companies can't afford to create life-saving drugs
- PMID: 32814891
- DOI: 10.1038/d41586-020-02418-x
The antibiotic paradox: why companies can't afford to create life-saving drugs
Keywords: Antibiotics; Business; Diseases; Infection.
Similar articles
-
A three-step plan for antibiotics.Nature. 2014 May 29;509(7502):533. doi: 10.1038/509533a. Nature. 2014. PMID: 24877183 No abstract available.
-
Accelerating regulation in response to COVID-19.Bull World Health Organ. 2020 Aug 1;98(8):514-515. doi: 10.2471/BLT.20.020820. Bull World Health Organ. 2020. PMID: 32773895 Free PMC article.
-
COVID-vaccine results are on the way - and scientists' concerns are growing.Nature. 2020 Oct;586(7827):16-17. doi: 10.1038/d41586-020-02706-6. Nature. 2020. PMID: 32978611 No abstract available.
-
Novel approaches are needed to develop tomorrow's antibacterial therapies.Am J Respir Crit Care Med. 2015 Jan 15;191(2):135-40. doi: 10.1164/rccm.201410-1894OE. Am J Respir Crit Care Med. 2015. PMID: 25590154 Free PMC article. Review.
-
Prospects for productivity.Nat Rev Drug Discov. 2004 May;3(5):451-6. doi: 10.1038/nrd1384. Nat Rev Drug Discov. 2004. PMID: 15136792 Review. No abstract available.
Cited by
-
Evidence at time of regulatory approval and cost of new antibiotics in 2016-19: cohort study of FDA approved drugs.BMJ Med. 2022 Dec 12;1(1):e000227. doi: 10.1136/bmjmed-2022-000227. eCollection 2022. BMJ Med. 2022. PMID: 36936591 Free PMC article.
-
Metals to combat antimicrobial resistance.Nat Rev Chem. 2023 Mar;7(3):202-224. doi: 10.1038/s41570-023-00463-4. Epub 2023 Feb 8. Nat Rev Chem. 2023. PMID: 37117903 Free PMC article. Review.
-
Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA.Epigenetics. 2022 Sep;17(9):970-981. doi: 10.1080/15592294.2021.1976910. Epub 2021 Sep 15. Epigenetics. 2022. PMID: 34523387 Free PMC article.
-
Mechanistic Duality of Bacterial Efflux Substrates and Inhibitors: Example of Simple Substituted Cinnamoyl and Naphthyl Amides.ACS Infect Dis. 2021 Sep 10;7(9):2650-2665. doi: 10.1021/acsinfecdis.1c00100. Epub 2021 Aug 11. ACS Infect Dis. 2021. PMID: 34379382 Free PMC article.
-
Promising strategies employing nucleic acids as antimicrobial drugs.Mol Ther Nucleic Acids. 2024 Jan 18;35(1):102122. doi: 10.1016/j.omtn.2024.102122. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2024. PMID: 38333674 Free PMC article. Review.
References
-
- Shlaes, D. M. Antimicrob. Agents Chemother. 64, e02057-19 (2020). - DOI
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical