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Review
. 2020 Jun 15;26(6):13030/qt05f926n7.

Cutaneous Legionella infections in allogeneic hematopoietic cell transplantation recipients

Affiliations
Review

Cutaneous Legionella infections in allogeneic hematopoietic cell transplantation recipients

Toral Vaidya et al. Dermatol Online J. .

Abstract

To date, only twenty cases of cutaneous legionellosis have been reported. Cutaneous legionellosis has heterogeneous manifestations including abscesses, nodules, and cellulitis. The detection of most cutaneous Legionella species requires specific diagnostic cultures and assays. Herein, we report a case of cutaneous legionella in a hematopoietic cell transplantation recipient with culture-negative nodules unresponsive to empiric antibiotics. We also discuss the varied morphology of cutaneous legionellosis and important diagnostic considerations.

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Figures

Figure 1.
Figure 1.
Clinical presentation of cutaneous legionellosis in a 50-year-old female with painful erythematous, compressible nodules.
Figure 2.
Figure 2.
A) Diffuse predominantly neutrophilic inflammatory infiltrate is present in dermis. H&E, 30×. B) Higher magnification showing neutrophils, fibrinoid debris, and possible bacterial forms (arrow). H&E, 600×. C) Brown-Hopps stain highlights a cluster of gram-negative rods (inset), 600×.

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