Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Dec;41(12):2206-2208.
doi: 10.3174/ajnr.A6762. Epub 2020 Aug 13.

COVID-19-Associated PRES-like Encephalopathy with Perivascular Gadolinium Enhancement

G Conte  1 , S Avignone  2 , M Carbonara  3 , M Meneri  4 , F Ortolano  3 , C Cinnante  2 , F Triulzi  2
Affiliations
Case Reports

COVID-19-Associated PRES-like Encephalopathy with Perivascular Gadolinium Enhancement

G Conte et al. AJNR Am J Neuroradiol. 2020 Dec.

Abstract

We describe the case of a 63-year-old woman who developed a coronavirus disease 2019-associated acute encephalopathy with perivascular gadolinium enhancement.

PubMed Disclaimer

Figures

FIG 1.
FIG 1.
The FLAIR sequence shows multiple lesions of the white matter of both hemispheres (A–C), more striking in the posterior regions with a tumefactive appearance (long arrows) and with a multifocal perivascular pattern in the deep white matter regions (short arrows). The lesions (arrows) show high values on the apparent diffusion coefficient map (D), suggesting increased water content in the parenchyma. The SWI sequence (E) shows a subarachnoid blood effusion along the left precentral sulcus (arrow). MR venography (F) excludes intracranial thrombosis.
FIG 2.
FIG 2.
The contrast-enhanced 3D conventional T1-weighted sequence (A–C) shows multiple spotlike gadolinium enhancement (arrows) in the posterior white matter and left hemisphere. The postcontrast 3D-T1-weighted black-blood sequence (D–F) shows a stratiform perivascular gadolinium enhancement in the white matter of both cerebral hemispheres. Neither wall enhancement of the large intracranial arterial vessels nor leptomeningeal enhancement are observed on postcontrast sequences.
See this image and copyright information in PMC

References

    1. Bartynski WS. Posterior reversible encephalopathy syndrome, Part 1: fundamental imaging and clinical features. AJNR Am J Neuroradiol 2008;29:1036–42 10.3174/ajnr.A0928 - DOI - PMC - PubMed
    1. Saad AF, Chaudhari R, Wintermark M. Imaging of atypical and complicated posterior reversible encephalopathy syndrome. Front Neurol 2019;10:964 10.3389/fneur.2019.00964 - DOI - PMC - PubMed
    1. Fugate JE, Rabinstein AA. Posterior reversible encephalopathy syndrome: clinical and radiological manifestations, pathophysiology, and outstanding questions. Lancet Neurol 2015;14:914–25 10.1016/S1474-4422(15)00111-8 - DOI - PubMed

Publication types