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Review
. 2021 Feb 1;47(2):245-255.
doi: 10.1097/j.jcrs.0000000000000364.

Measures of visual disturbance in patients receiving extended depth-of-focus or trifocal intraocular lenses

Thomas Kohnen  1 , Rajaraman Suryakumar
Affiliations
Review

Measures of visual disturbance in patients receiving extended depth-of-focus or trifocal intraocular lenses

Thomas Kohnen et al. J Cataract Refract Surg. .

Abstract

The degree of visual disturbance associated with a particular model of intraocular lens (IOL) depends on several factors, including IOL optic, material, and mechanics. Characterization of visual disturbance profiles is paramount for informing clinical IOL selection. Although many studies evaluating presbyopia-correcting IOLs include subjective assessment of visual symptoms, the types of patient-reported outcome measures (PROMs) used to capture these outcomes are inconsistent across studies, complicating data contextualization. Furthermore, some tools produce more meaningful results than others. This review presents a discussion on the scientific literature published on the subjective and semiobjective (halo and glare simulator, light-distortion analyzer, vision monitor, and halometers) methods used to assess visual disturbances in patients implanted with trifocal or extended depth-of-focus IOLs, highlighting their advantages and limitations. It underscores the importance of between-study comparisons and the need for standardized PROMs in clinical IOL research to provide more accurate information for IOL selection.

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References

    1. Galor A, Gonzalez M, Goldman D, O'Brien TP. Intraocular lens exchange surgery in dissatisfied patients with refractive intraocular lenses. J Cataract Refract Surg 2009;35:1706–1710
    1. de Vries NE, Webers CA, Touwslager WR, Bauer NJ, de Brabander J, Berendschot TT, Nuijts RM. Dissatisfaction after implantation of multifocal intraocular lenses. J Cataract Refract Surg 2011;37:859–865
    1. McAlinden C, Pesudovs K, Moore JE. The development of an instrument to measure quality of vision: the Quality of Vision (QoV) questionnaire. Invest Ophthalmol Vis Sci 2010;51:5537–5545
    1. Braithwaite T, Calvert M, Gray A, Pesudovs K, Denniston AK. The use of patient-reported outcome research in modern ophthalmology: impact on clinical trials and routine clinical practice. Patient Relat Outcome Meas 2019;10:9–24
    1. de Silva SR, Evans JR, Kirthi V, Ziaei M, Leyland M. Multifocal versus monofocal intraocular lenses after cataract extraction. Cochrane Database Syst Rev 2016;12:CD003169

OTHER CITED MATERIALS

    1. U.S. Food and Drug Administration. Patient-reported outcomes (PROs) in medical device decision making. Available at: https://www.fda.gov/about-fda/cdrh-patient-engagement/patient-reported-o... . Accessed May 21, 2019
    1. U.S. Food and Drug Administration. Patient-focused drug development: collecting comprehensive and representative input. Available at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents... . Accessed May 21, 2019
    1. U.S. Food and Drug Administration. Guidance for industry patient-reported outcome measures: use in medical product development to support labeling claims. Available at: https://www.regulations.gov/contentStreamer?documentId=FDA-2006-D-0362-0... . Accessed January 3, 2020
    1. Precision Lens. Products: Tecnis Symfony toric extended depth of focus IOL model ZXT (150, 225, 300, 375). Available at: http://www.precisionlens.net/tecnis-symfony-toric-extended-depth-of-focu... . Accessed May 16, 2019
    1. Alcon Vision LLC. Product Information: AcrySof™ IQ Vivity™ Extended Vision IOL

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