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. 1988 Apr 28;332(6167):805-10.
doi: 10.1038/332805a0.

70K heat shock related proteins stimulate protein translocation into microsomes

W J Chirico  1 , M G Waters, G Blobel
Affiliations

70K heat shock related proteins stimulate protein translocation into microsomes

W J Chirico et al. Nature. .

Abstract

A yeast cytosol is shown to contain two distinct activities that stimulate protein translocation across microsomal membranes. One activity was purified. It consists of two constitutively expressed 70K heat shock related proteins that increase the rate of translocation. Possible mechanisms of action of these proteins are discussed.

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