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Comment
. 2020 Aug 20;182(4):796-798.
doi: 10.1016/j.cell.2020.07.042.

Myeloid Cells TREM Down Anti-tumor Responses

Aimée Bugler-Lamb  1 , Martin Guilliams  2
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Myeloid Cells TREM Down Anti-tumor Responses

Aimée Bugler-Lamb et al. Cell. .
Free article

Abstract

In this issue of Cell, Molgora et al. and Katzenelenbogen, Sheban, Yalin, et al. highlight the novel role of TREM2 in shaping the immunosuppressive profile of tumor-associated myeloid cells and report that complementing immune-checkpoint therapy with TREM2 blockade induces stronger anti-tumor immune responses and reduces tumor growth.

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